Detailed information    

insolico Bioinformatically predicted

Overview

Name   cipB   Type   Regulator
Locus tag   AAIS09_RS02455 Genome accession   NZ_CP154595
Coordinates   477501..477650 (+) Length   49 a.a.
NCBI ID   WP_001818346.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain serotype 4     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 475911..476634 477501..477650 flank 867


Gene organization within MGE regions


Location: 475911..477650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAIS09_RS02445 (AAIS09_02440) blpM 476784..477038 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  AAIS09_RS02450 (AAIS09_02445) blpN 477054..477257 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  AAIS09_RS02455 (AAIS09_02450) cipB 477501..477650 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator

Sequence

Protein


Download         Length: 49 a.a.        Molecular weight: 5134.91 Da        Isoelectric Point: 3.9133

>NTDB_id=993669 AAIS09_RS02455 WP_001818346.1 477501..477650(+) (cipB) [Streptococcus pneumoniae strain serotype 4]
MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=993669 AAIS09_RS02455 WP_001818346.1 477501..477650(+) (cipB) [Streptococcus pneumoniae strain serotype 4]
ATGGATACAAAAATGATGTCACAATTTGCAGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA

Domains

Predicted by InterproScan.

Bacteriocin class II with double-glycine leader peptide (Bacteriocin_IIc)

(6-44)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

51.02

100

0.51

Multiple sequence alignment