Detailed information NTG0993501

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: E0E10_RS11380
• Genome accession: NZ_LR027878
• Coordinates: 2155298..2156011 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain BPH2003 isolate BPH2003
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2150298..2161011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0E10_RS11315	-	2151053..2151316 (-)	264	WP_001205732.1	hypothetical protein	-
E0E10_RS11320	-	2151325..2151585 (-)	261	WP_001814567.1	DUF1108 family protein	-
E0E10_RS11325	-	2151566..2151895 (-)	330	WP_000138304.1	hypothetical protein	-
E0E10_RS11330	-	2151985..2152146 (-)	162	WP_000066017.1	DUF1270 domain-containing protein	-
E0E10_RS11335	-	2152143..2152463 (-)	321	WP_001120197.1	DUF771 domain-containing protein	-
E0E10_RS11340	-	2152522..2153154 (+)	633	WP_000275058.1	hypothetical protein	-
E0E10_RS11345	-	2153169..2153309 (-)	141	WP_000939496.1	hypothetical protein	-
E0E10_RS11350	-	2153340..2153537 (-)	198	WP_001148861.1	hypothetical protein	-
E0E10_RS11355	-	2153553..2154302 (-)	750	WP_001148653.1	phage antirepressor KilAC domain-containing protein	-
E0E10_RS11360	-	2154353..2154682 (+)	330	WP_000180411.1	hypothetical protein	-
E0E10_RS11365	-	2154671..2154886 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
E0E10_RS11370	-	2154902..2155165 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
E0E10_RS11375	-	2155162..2155335 (-)	174	WP_001801500.1	hypothetical protein	-
E0E10_RS11380	irvR	2155298..2156011 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
E0E10_RS11385	-	2156027..2156959 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
E0E10_RS11390	-	2156965..2157306 (+)	342	WP_000591749.1	hypothetical protein	-
E0E10_RS11395	-	2157510..2157692 (+)	183	WP_000705248.1	hypothetical protein	-
E0E10_RS11400	-	2157792..2158256 (+)	465	WP_000825947.1	hypothetical protein	-
E0E10_RS11405	-	2158315..2159352 (+)	1038	WP_000857191.1	tyrosine-type recombinase/integrase	-
E0E10_RS11410	sph	2159409..2160233 (+)	825	Protein_2107	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=993501 E0E10_RS11380 WP_001031454.1 2155298..2156011(+) (irvR) [Staphylococcus aureus strain BPH2003 isolate BPH2003]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=993501 E0E10_RS11380 WP_001031454.1 2155298..2156011(+) (irvR) [Staphylococcus aureus strain BPH2003 isolate BPH2003]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401