Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E0E12_RS06605 Genome accession   NZ_LR027876
Coordinates   1286581..1287354 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain JKD6009 isolate JKD6009     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1281581..1292354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E12_RS06585 trmFO 1281925..1283232 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  E0E12_RS06590 xerC 1283649..1284545 (+) 897 WP_001015597.1 tyrosine recombinase XerC -
  E0E12_RS06595 hslV 1284542..1285087 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  E0E12_RS06600 hslU 1285153..1286556 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  E0E12_RS06605 codY 1286581..1287354 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E0E12_RS06610 - 1287405..1287497 (+) 93 WP_001790530.1 hypothetical protein -
  E0E12_RS06615 rpsB 1287696..1288463 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  E0E12_RS06620 - 1288497..1288610 (+) 114 WP_001789890.1 hypothetical protein -
  E0E12_RS06625 tsf 1288645..1289526 (+) 882 WP_000201387.1 translation elongation factor Ts -
  E0E12_RS06630 pyrH 1289663..1290385 (+) 723 WP_000057330.1 UMP kinase -
  E0E12_RS06635 frr 1290404..1290958 (+) 555 WP_001280006.1 ribosome recycling factor -
  E0E12_RS06640 - 1291331..1292101 (+) 771 WP_000473701.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=993284 E0E12_RS06605 WP_000055337.1 1286581..1287354(+) (codY) [Staphylococcus aureus strain JKD6009 isolate JKD6009]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=993284 E0E12_RS06605 WP_000055337.1 1286581..1287354(+) (codY) [Staphylococcus aureus strain JKD6009 isolate JKD6009]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment