Detailed information NTG0993236

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: E0E13_RS10995
• Genome accession: NZ_LR027874
• Coordinates: 2107156..2107863 (+)
• Length: 235 a.a.
• NCBI ID: WP_000094093.1
• Uniprot ID: A0A1D4DWM6
• Organism: Staphylococcus aureus strain BPH2056 isolate BPH2056
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2102156..2112863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0E13_RS10940	-	2102910..2103173 (-)	264	WP_001205732.1	hypothetical protein	-
E0E13_RS10945	-	2103182..2103442 (-)	261	WP_000291489.1	DUF1108 family protein	-
E0E13_RS10950	-	2103535..2103696 (-)	162	WP_000066020.1	DUF1270 domain-containing protein	-
E0E13_RS10955	-	2103693..2104013 (-)	321	WP_001120197.1	DUF771 domain-containing protein	-
E0E13_RS10960	-	2104072..2104704 (+)	633	WP_000275058.1	hypothetical protein	-
E0E13_RS10965	-	2104719..2104859 (-)	141	WP_000939496.1	hypothetical protein	-
E0E13_RS10970	-	2104890..2105084 (-)	195	WP_000388066.1	hypothetical protein	-
E0E13_RS10975	-	2105101..2105853 (-)	753	WP_001148618.1	phage antirepressor KilAC domain-containing protein	-
E0E13_RS10980	-	2105910..2106449 (+)	540	WP_000351243.1	hypothetical protein	-
E0E13_RS10985	-	2106473..2106733 (-)	261	WP_000435341.1	transcriptional regulator	-
E0E13_RS10990	-	2106746..2106985 (-)	240	WP_000548578.1	helix-turn-helix transcriptional regulator	-
E0E13_RS10995	irvR	2107156..2107863 (+)	708	WP_000094093.1	helix-turn-helix domain-containing protein	Regulator
E0E13_RS15975	-	2107875..2108030 (+)	156	WP_001049399.1	hypothetical protein	-
E0E13_RS11000	-	2108017..2108202 (+)	186	WP_001089804.1	hypothetical protein	-
E0E13_RS11005	-	2108402..2108569 (+)	168	WP_000705238.1	hypothetical protein	-
E0E13_RS11010	-	2108709..2109248 (+)	540	WP_000391618.1	type II toxin-antitoxin system PemK/MazF family toxin	-
E0E13_RS11015	-	2109421..2110458 (+)	1038	WP_000857198.1	tyrosine-type recombinase/integrase	-
E0E13_RS11020	sph	2110515..2111339 (+)	825	Protein_2037	sphingomyelin phosphodiesterase	-
E0E13_RS11025	lukG	2111577..2112593 (-)	1017	WP_000595323.1	bi-component leukocidin LukGH subunit G	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26769.35 Da
• Isoelectric Point: 5.4082

>NTDB_id=993236 E0E13_RS10995 WP_000094093.1 2107156..2107863(+) (irvR) [Staphylococcus aureus strain BPH2056 isolate BPH2056]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide

• Length: 708 bp

>NTDB_id=993236 E0E13_RS10995 WP_000094093.1 2107156..2107863(+) (irvR) [Staphylococcus aureus strain BPH2056 isolate BPH2056]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (123-234)

• Helix-turn-helix (HTH_3) (8-61)

3D structure

• AlphaFold DB: A0A1D4DWM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	30.769	100	0.374