Detailed information NTG0993172

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ77_RS14340
• Genome accession: NZ_CP154385
• Coordinates: 2815970..2816857 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN30
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2810970..2821857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ77_RS14310 (UXQ77_14315)	-	2810989..2811081 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ77_RS14315 (UXQ77_14320)	-	2811189..2811686 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXQ77_RS14320 (UXQ77_14325)	-	2811696..2811956 (-)	261	WP_001789910.1	hypothetical protein	-
UXQ77_RS14325 (UXQ77_14330)	-	2812338..2812451 (-)	114	WP_001791776.1	hypothetical protein	-
UXQ77_RS14330 (UXQ77_14335)	-	2813110..2815110 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXQ77_RS14335 (UXQ77_14340)	-	2815107..2815862 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ77_RS14340 (UXQ77_14345)	braS	2815970..2816857 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ77_RS14345 (UXQ77_14350)	braR	2816868..2817533 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ77_RS14350 (UXQ77_14355)	-	2817559..2817759 (-)	201	WP_000604728.1	hypothetical protein	-
UXQ77_RS14355 (UXQ77_14360)	-	2817957..2819381 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXQ77_RS14360 (UXQ77_14365)	-	2819451..2819561 (+)	111	WP_001791296.1	hypothetical protein	-
UXQ77_RS14365 (UXQ77_14370)	-	2819664..2820119 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ77_RS14370 (UXQ77_14375)	-	2820364..2821125 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=993172 UXQ77_RS14340 WP_000143419.1 2815970..2816857(-) (braS) [Staphylococcus aureus strain BSN30]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=993172 UXQ77_RS14340 WP_000143419.1 2815970..2816857(-) (braS) [Staphylococcus aureus strain BSN30]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997