Detailed information NTG0993167

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ77_RS10415
• Genome accession: NZ_CP154385
• Coordinates: 2072094..2073137 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN30
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2067094..2078137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ77_RS10385 (UXQ77_10390)	-	2067512..2068768 (-)	1257	WP_001795438.1	aminopeptidase	-
UXQ77_RS10390 (UXQ77_10395)	-	2068771..2068971 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXQ77_RS10395 (UXQ77_10400)	-	2069118..2069582 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ77_RS10400 (UXQ77_10405)	-	2069589..2069864 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ77_RS10405 (UXQ77_10410)	-	2070142..2071359 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ77_RS10410 (UXQ77_10415)	vraR	2071475..2072104 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ77_RS10415 (UXQ77_10420)	vraS	2072094..2073137 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ77_RS10420 (UXQ77_10425)	liaF	2073134..2073835 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ77_RS10425 (UXQ77_10430)	-	2073850..2074236 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ77_RS10430 (UXQ77_10435)	map	2074453..2075211 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ77_RS10435 (UXQ77_10440)	-	2075739..2076725 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ77_RS10440 (UXQ77_10445)	-	2077215..2077628 (-)	414	WP_001549145.1	hypothetical protein	-
UXQ77_RS10445 (UXQ77_10450)	-	2077657..2077767 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=993167 UXQ77_RS10415 WP_001017131.1 2072094..2073137(-) (vraS) [Staphylococcus aureus strain BSN30]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=993167 UXQ77_RS10415 WP_001017131.1 2072094..2073137(-) (vraS) [Staphylococcus aureus strain BSN30]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1