Detailed information NTG0993061

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AAIB43_RS04865
• Genome accession: NZ_CP154366
• Coordinates: 1032539..1033582 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain 14BME10
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1027539..1038582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAIB43_RS04840 (AAIB43_04845)	-	1028493..1029215 (+)	723	WP_042362406.1	glutamine amidotransferase	-
AAIB43_RS04845 (AAIB43_04850)	-	1029418..1030404 (-)	987	WP_042362407.1	aromatic acid exporter family protein	-
AAIB43_RS04850 (AAIB43_04855)	map	1030581..1031333 (+)	753	WP_069796260.1	type I methionyl aminopeptidase	-
AAIB43_RS04855 (AAIB43_04860)	-	1031438..1031824 (+)	387	WP_042362408.1	hypothetical protein	-
AAIB43_RS04860 (AAIB43_04865)	liaF	1031841..1032542 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
AAIB43_RS04865 (AAIB43_04870)	vraS	1032539..1033582 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
AAIB43_RS04870 (AAIB43_04875)	vraR	1033572..1034201 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
AAIB43_RS04875 (AAIB43_04880)	-	1034470..1035615 (-)	1146	WP_042362411.1	YihY/virulence factor BrkB family protein	-
AAIB43_RS04880 (AAIB43_04885)	-	1035971..1036255 (-)	285	WP_042362412.1	hypothetical protein	-
AAIB43_RS04885 (AAIB43_04890)	-	1036262..1036726 (-)	465	WP_029378983.1	low molecular weight protein-tyrosine-phosphatase	-
AAIB43_RS04890 (AAIB43_04895)	-	1036861..1037064 (+)	204	WP_017723498.1	DUF1128 family protein	-
AAIB43_RS04895 (AAIB43_04900)	-	1037082..1038320 (+)	1239	WP_343323119.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=993061 AAIB43_RS04865 WP_042362410.1 1032539..1033582(+) (vraS) [Staphylococcus xylosus strain 14BME10]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=993061 AAIB43_RS04865 WP_042362410.1 1032539..1033582(+) (vraS) [Staphylococcus xylosus strain 14BME10]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTAGCACGTGAATTACATGATTCAGTGAGT
CAGCAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAGGCACCTCTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGACTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACAAAAGTAACTATAGAGTTATTTAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTACCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885