Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA/pilA1   Type   Machinery gene
Locus tag   TTHNP4_RS02285 Genome accession   NZ_LR027517
Coordinates   409108..409581 (-) Length   157 a.a.
NCBI ID   WP_124104350.1    Uniprot ID   -
Organism   Thermus thermophilus isolate TTHNAR1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 404108..414581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTHNP4_RS02260 (TTHN1_00453) - 404597..405022 (-) 426 WP_124104346.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  TTHNP4_RS02265 (TTHN1_00454) comZ 405238..406914 (-) 1677 WP_124104347.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  TTHNP4_RS02270 (TTHN1_00455) pilA/pilA3 406925..407626 (-) 702 WP_124104348.1 PilW family protein Machinery gene
  TTHNP4_RS02275 (TTHN1_00456) pilA/pilA2 407623..408129 (-) 507 WP_252973319.1 prepilin Machinery gene
  TTHNP4_RS14420 (TTHN1_00457) - 408699..408962 (+) 264 WP_252973320.1 hypothetical protein -
  TTHNP4_RS02285 (TTHN1_00458) pilA/pilA1 409108..409581 (-) 474 WP_124104350.1 GspH/FimT family protein Machinery gene
  TTHNP4_RS02290 (TTHN1_00459) pilA/pilA1 409637..410107 (-) 471 WP_124104351.1 GspH/FimT family protein Machinery gene
  TTHNP4_RS02295 (TTHN1_00460) - 410265..411245 (+) 981 WP_124104352.1 YpdA family putative bacillithiol disulfide reductase -
  TTHNP4_RS02305 (TTHN1_00461) ilvB 411401..413089 (+) 1689 WP_124104353.1 biosynthetic-type acetolactate synthase large subunit -
  TTHNP4_RS02310 (TTHN1_00462) ilvN 413086..413598 (+) 513 WP_011173280.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 16770.15 Da        Isoelectric Point: 10.9215

>NTDB_id=992861 TTHNP4_RS02285 WP_124104350.1 409108..409581(-) (pilA/pilA1) [Thermus thermophilus isolate TTHNAR1]
MRKPHGLSLIELVIVLAVLGVLLALGTGYLRSDRLQVNQAARSLAAQVTRARLEAIRRNDFVGIQFLTSGTGGYVVFADQ
NRNRTYDAGDTAIQTVNFGQGEWARVRLTALAGPAALVFDPRGIPQDFTGATVTLSDRAGTYTKGVSLSPQGRASLP

Nucleotide


Download         Length: 474 bp        

>NTDB_id=992861 TTHNP4_RS02285 WP_124104350.1 409108..409581(-) (pilA/pilA1) [Thermus thermophilus isolate TTHNAR1]
ATGAGGAAGCCCCATGGCCTAAGCCTCATAGAGCTCGTGATCGTTCTCGCCGTCCTGGGGGTCCTCCTGGCCCTGGGCAC
GGGCTACTTGCGCTCCGACCGCCTCCAGGTGAACCAGGCGGCCCGCTCCCTCGCCGCCCAGGTGACCCGGGCGAGGCTCG
AGGCCATCCGCCGGAACGACTTTGTGGGGATCCAGTTCCTCACCAGCGGGACAGGGGGGTACGTGGTCTTCGCGGACCAG
AACCGGAACCGCACCTACGACGCGGGGGACACCGCCATCCAGACGGTGAACTTCGGGCAGGGGGAGTGGGCCCGGGTGCG
GCTTACCGCCCTCGCAGGCCCCGCGGCCCTGGTCTTTGACCCCCGGGGCATCCCGCAAGACTTCACGGGAGCGACCGTGA
CCCTAAGCGACCGTGCCGGAACCTACACCAAAGGGGTTTCCCTAAGCCCCCAGGGGAGGGCGAGCCTGCCATGA

Domains

Predicted by InterProScan.

Type II transport protein GspH (GspH)

(40-152)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-25)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA/pilA1 Thermus thermophilus HB27

55.906

80.892

0.452

Multiple sequence alignment