Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKTXI_RS20025 Genome accession   NZ_AP035884
Coordinates   4487231..4487875 (-) Length   214 a.a.
NCBI ID   WP_030078218.1    Uniprot ID   A0ABW2MPR0
Organism   Streptomyces sp. CMC78     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4482231..4492875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTXI_RS20000 (SCMC78_40540) - 4483013..4483504 (+) 492 WP_319597897.1 GNAT family N-acetyltransferase -
  ACKTXI_RS20005 (SCMC78_40550) - 4483545..4484543 (-) 999 WP_398693528.1 zinc-binding dehydrogenase -
  ACKTXI_RS20010 (SCMC78_40560) - 4484626..4485819 (-) 1194 WP_319597899.1 NAD(P)-binding protein -
  ACKTXI_RS20015 (SCMC78_40570) - 4485923..4486633 (+) 711 WP_319597900.1 pentapeptide repeat-containing protein -
  ACKTXI_RS20020 (SCMC78_40580) - 4486650..4487147 (-) 498 WP_319597901.1 hypothetical protein -
  ACKTXI_RS20025 (SCMC78_40590) vraR 4487231..4487875 (-) 645 WP_030078218.1 response regulator Regulator
  ACKTXI_RS20030 (SCMC78_40600) - 4487872..4489149 (-) 1278 WP_032790071.1 sensor histidine kinase -
  ACKTXI_RS20035 (SCMC78_40610) - 4489398..4489955 (+) 558 WP_319597902.1 GlcG/HbpS family heme-binding protein -
  ACKTXI_RS20040 (SCMC78_40620) - 4489990..4490586 (+) 597 WP_397724383.1 ankyrin repeat domain-containing protein -
  ACKTXI_RS20045 (SCMC78_40630) - 4490583..4491866 (+) 1284 WP_398693531.1 YncE family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 22754.07 Da        Isoelectric Point: 5.1153

>NTDB_id=99212 ACKTXI_RS20025 WP_030078218.1 4487231..4487875(-) (vraR) [Streptomyces sp. CMC78]
MTGQAPQTPPVRILLCDDHVVVRAGLLALLGSEPDIEVVGEAGSGEEAVVLAARLTPDVVLMDLQLGEGIDGVEATRRIA
ADGTVHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSAPVASRVMARMRSPRPTLTDRERDI
LAQLSQGLGNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 645 bp        

>NTDB_id=99212 ACKTXI_RS20025 WP_030078218.1 4487231..4487875(-) (vraR) [Streptomyces sp. CMC78]
ATGACCGGCCAGGCCCCGCAGACGCCCCCCGTACGGATCCTGCTCTGCGACGACCACGTGGTCGTCCGCGCCGGACTGCT
CGCCCTCCTCGGCAGCGAACCGGACATCGAGGTCGTCGGCGAGGCGGGCAGCGGCGAGGAGGCCGTGGTGCTCGCCGCCC
GCCTCACCCCGGACGTCGTCCTCATGGACCTGCAGCTCGGCGAGGGCATCGACGGCGTCGAGGCGACCCGCCGCATCGCG
GCCGACGGCACGGTCCACGTCCTGGTGCTGACCACGTACGACACCGACGCCGACATCACCCGCGCCATCGAGGCGGGCGC
CACCGGCTACCTGCTGAAGGCGGAACGCCCGGAGGAGCTCTTCGCCGCCATCCGCTCCGCAGCCCAGGGCCGCACCACCC
TCTCGGCCCCGGTCGCCAGCCGGGTCATGGCCCGCATGCGCAGCCCCCGCCCCACCCTGACCGACCGCGAACGCGACATC
CTGGCCCAGCTGTCCCAGGGCCTCGGCAACCGCGACATCGCCCGCGCCCTGTTCATCAGCGAGGCCACGGTCAAGACCCA
CCTGGGCCGCATCTACGACAAGCTCGGCGTCGACACCCGCGCGGGCGCGGTGTCGGTGGCGAAGGAACAGCGGCTGCTGC
CTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-207)

Response regulator receiver domain (Response_reg)

(13-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.13

96.729

0.379

Multiple sequence alignment