Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKTXI_RS15925 Genome accession   NZ_AP035884
Coordinates   3552678..3553337 (+) Length   219 a.a.
NCBI ID   WP_030634174.1    Uniprot ID   A0ABW2MN34
Organism   Streptomyces sp. CMC78     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3547678..3558337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTXI_RS15910 (SCMC78_32370) - 3549065..3550162 (-) 1098 WP_050495824.1 methyltransferase -
  ACKTXI_RS15915 (SCMC78_32390) - 3550448..3551458 (+) 1011 WP_319597871.1 hypothetical protein -
  ACKTXI_RS15920 (SCMC78_32400) - 3551437..3552681 (+) 1245 WP_319597872.1 sensor histidine kinase -
  ACKTXI_RS15925 (SCMC78_32410) vraR 3552678..3553337 (+) 660 WP_030634174.1 response regulator Regulator
  ACKTXI_RS15930 (SCMC78_32420) - 3553355..3553927 (-) 573 WP_247595107.1 YbaK/EbsC family protein -
  ACKTXI_RS15935 (SCMC78_32430) - 3553924..3555159 (-) 1236 WP_319597873.1 cytochrome P450 family protein -
  ACKTXI_RS15940 (SCMC78_32440) - 3555175..3556140 (-) 966 WP_319597874.1 ATP-binding cassette domain-containing protein -
  ACKTXI_RS15945 (SCMC78_32450) - 3556137..3557456 (-) 1320 WP_319597875.1 cytochrome P450 family protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23734.38 Da        Isoelectric Point: 4.9916

>NTDB_id=99203 ACKTXI_RS15925 WP_030634174.1 3552678..3553337(+) (vraR) [Streptomyces sp. CMC78]
MTIRVFLVDDQEMVRAGFVMVVEAQDDMTVVGQAGDGAEALEKLAVTSADIVLMDVRMPRMDGVEATRRLLARADAPKVV
VLTTFDVDEHAFAALQAGASGFLVKDAPAEDLLSAIRTVQRGDAVISPTTTRRLLDEVAPDLPQRSEGPDPLAELTARER
EVLLLIARGASNAAIGKELHLSEGTVKTHVGRLLAKLGMRDRVQVVIFAYEQRLVRPGR

Nucleotide


Download         Length: 660 bp        

>NTDB_id=99203 ACKTXI_RS15925 WP_030634174.1 3552678..3553337(+) (vraR) [Streptomyces sp. CMC78]
ATGACGATCCGGGTGTTCCTCGTCGACGACCAGGAGATGGTGCGGGCCGGCTTCGTCATGGTCGTCGAGGCGCAGGACGA
CATGACGGTGGTCGGCCAGGCGGGCGACGGCGCGGAGGCGCTGGAGAAGCTGGCCGTGACCTCCGCCGACATCGTGCTGA
TGGACGTCCGGATGCCGCGCATGGACGGCGTGGAGGCGACCCGCAGACTGCTGGCGCGCGCCGACGCGCCGAAGGTCGTC
GTGCTCACCACCTTCGACGTCGACGAGCACGCCTTCGCCGCGCTCCAGGCCGGGGCCAGCGGCTTCCTGGTCAAGGACGC
CCCGGCCGAGGACCTGCTCTCCGCGATCCGCACCGTTCAGCGCGGCGACGCGGTCATCTCGCCGACCACCACCCGGCGGC
TGCTCGACGAGGTCGCGCCGGACCTGCCGCAGCGCAGCGAAGGACCGGACCCGCTGGCCGAGCTCACCGCCCGCGAGCGC
GAGGTCCTGCTGCTCATCGCGCGCGGCGCGTCGAACGCCGCCATCGGCAAGGAACTGCATCTGTCCGAGGGCACGGTGAA
GACGCACGTCGGACGGCTGCTGGCGAAGCTCGGCATGCGCGACCGCGTGCAGGTGGTGATCTTCGCCTACGAGCAGCGGC
TGGTCCGCCCGGGGCGCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.096

100

0.411

Multiple sequence alignment