Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   A66_RS00900 Genome accession   NZ_LN847353
Coordinates   167765..168205 (-) Length   146 a.a.
NCBI ID   WP_053039431.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain A66     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 162765..173205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS00875 (A66_00172) - 163026..164312 (+) 1287 WP_000278876.1 response regulator transcription factor -
  A66_RS00880 (A66_00173) - 164364..164897 (+) 534 WP_000729030.1 hypothetical protein -
  A66_RS00885 (A66_00174) nrdI 164975..165445 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  A66_RS00890 (A66_00175) - 165738..167000 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  A66_RS00895 (A66_00176) - 167310..167768 (-) 459 WP_000745053.1 DUF3021 domain-containing protein -
  A66_RS00900 (A66_00177) brsR 167765..168205 (-) 441 WP_053039431.1 LytTR family DNA-binding domain-containing protein Regulator
  A66_RS00905 (A66_00178) hexB 168411..170360 (+) 1950 WP_000018159.1 DNA mismatch repair endonuclease MutL Machinery gene
  A66_RS00910 (A66_00179) ribE 170685..171152 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  A66_RS00915 (A66_00180) - 171153..172358 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  A66_RS00920 (A66_00181) ribE 172378..173013 (-) 636 WP_000493841.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17139.83 Da        Isoelectric Point: 5.9842

>NTDB_id=991934 A66_RS00900 WP_053039431.1 167765..168205(-) (brsR) [Streptococcus pneumoniae strain A66]
MKVELQISETYEEEKLIVQAPQETEKIQKVIEFAENLDQRGKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQILKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=991934 A66_RS00900 WP_053039431.1 167765..168205(-) (brsR) [Streptococcus pneumoniae strain A66]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAAT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGGAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGATTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment