Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   A66_RS00245 Genome accession   NZ_LN847353
Coordinates   39808..40701 (+) Length   297 a.a.
NCBI ID   WP_000343888.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain A66     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 34808..45701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A66_RS00205 (A66_00041) - 35121..36290 (+) 1170 WP_000366378.1 pyridoxal phosphate-dependent aminotransferase -
  A66_RS00210 (A66_00042) recO 36287..37057 (+) 771 WP_000616164.1 DNA repair protein RecO Machinery gene
  A66_RS00215 (A66_00043) plsX 37054..38046 (+) 993 WP_000717458.1 phosphate acyltransferase PlsX -
  A66_RS00220 (A66_00044) - 38052..38285 (+) 234 WP_000136447.1 acyl carrier protein -
  A66_RS00225 (A66_00045) - 38322..38621 (+) 300 Protein_40 transposase family protein -
  A66_RS00230 (A66_00046) blpU 38824..39054 (+) 231 WP_001093487.1 bacteriocin-like peptide BlpU -
  A66_RS12705 (A66_00047) - 39057..39182 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  A66_RS12325 - 39593..39787 (+) 195 WP_000756776.1 hypothetical protein -
  A66_RS00245 (A66_00048) comR 39808..40701 (+) 894 WP_000343888.1 XRE family transcriptional regulator Regulator
  A66_RS00250 (A66_00049) - 41244..41540 (+) 297 WP_000837726.1 uberolysin/carnocyclin family circular bacteriocin -
  A66_RS00255 (A66_00050) - 41547..42683 (+) 1137 WP_000698828.1 hypothetical protein -
  A66_RS10520 - 42680..43162 (+) 483 WP_001232094.1 stage II sporulation protein M -
  A66_RS00265 (A66_00051) - 43159..43755 (+) 597 WP_000687787.1 ATP-binding cassette domain-containing protein -
  A66_RS00270 - 43736..44227 (+) 492 WP_000671990.1 hypothetical protein -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 34517.01 Da        Isoelectric Point: 4.6498

>NTDB_id=991930 A66_RS00245 WP_000343888.1 39808..40701(+) (comR) [Streptococcus pneumoniae strain A66]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=991930 A66_RS00245 WP_000343888.1 39808..40701(+) (comR) [Streptococcus pneumoniae strain A66]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAAGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(76-289)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

36.667

100

0.37