Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   AT689_RS08275 Genome accession   NZ_LN831051
Coordinates   1561055..1561519 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1556055..1566519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS08255 (ERS445053_01616) - 1557006..1557974 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  AT689_RS08260 (ERS445053_01617) pdrM 1558128..1559489 (-) 1362 WP_000278534.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  AT689_RS08265 (ERS445053_01618) - 1559500..1559760 (-) 261 WP_001105925.1 hypothetical protein -
  AT689_RS08270 (ERS445053_01619) - 1559774..1561042 (-) 1269 WP_000924489.1 dihydroorotase -
  AT689_RS08275 (ERS445053_01620) mutX 1561055..1561519 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  AT689_RS08280 (ERS445053_01621) - 1561529..1562182 (-) 654 WP_000401329.1 uracil-DNA glycosylase -
  AT689_RS08285 (ERS445053_01622) - 1562320..1562967 (-) 648 WP_001809355.1 hypothetical protein -
  AT689_RS08290 (ERS445053_01623) - 1562981..1563694 (-) 714 WP_000499437.1 YjjG family noncanonical pyrimidine nucleotidase -
  AT689_RS12595 dhaM 1564152..1564532 (-) 381 Protein_1565 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  AT689_RS13715 - 1564532..1564606 (-) 75 Protein_1566 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=991817 AT689_RS08275 WP_001135768.1 1561055..1561519(-) (mutX) [Streptococcus pneumoniae strain NCTC7465]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=991817 AT689_RS08275 WP_001135768.1 1561055..1561519(-) (mutX) [Streptococcus pneumoniae strain NCTC7465]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987