Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   AT689_RS04190 Genome accession   NZ_LN831051
Coordinates   781312..782820 (+) Length   502 a.a.
NCBI ID   WP_001280730.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 776312..787820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS04155 (ERS445053_00807) yidC 776820..777746 (-) 927 WP_000835941.1 membrane protein insertase YidC -
  AT689_RS04160 (ERS445053_00808) - 777824..778102 (-) 279 WP_001174613.1 acylphosphatase -
  AT689_RS04165 (ERS445053_00809) - 778136..778876 (+) 741 WP_000152700.1 RNA methyltransferase -
  AT689_RS04170 (ERS445053_00810) - 778932..779615 (+) 684 WP_001016917.1 Bax inhibitor-1/YccA family protein -
  AT689_RS04175 (ERS445053_00811) asnA 779726..780718 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  AT689_RS04180 (ERS445053_00812) rsmD 780783..781322 (+) 540 WP_000706967.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AT689_RS04190 (ERS445053_00813) sepM 781312..782820 (+) 1509 WP_001280730.1 SepM family pheromone-processing serine protease Regulator
  AT689_RS04195 (ERS445053_00814) - 782878..783108 (+) 231 WP_000250393.1 DUF1146 family protein -
  AT689_RS04200 (ERS445053_00815) murA 783132..784415 (+) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AT689_RS04205 (ERS445053_00816) - 784408..784596 (+) 189 WP_001818955.1 DNA-directed RNA polymerase subunit beta -
  AT689_RS04210 (ERS445053_00817) endA 784635..785459 (+) 825 WP_001036790.1 DNA-entry nuclease EndA Machinery gene
  AT689_RS04215 (ERS445053_00818) - 785750..787081 (+) 1332 WP_000390039.1 hemolysin family protein -

Sequence

Protein


Download         Length: 502 a.a.        Molecular weight: 55359.68 Da        Isoelectric Point: 5.1375

>NTDB_id=991771 AT689_RS04190 WP_001280730.1 781312..782820(+) (sepM) [Streptococcus pneumoniae strain NCTC7465]
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVA
KRLGATCLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
KIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIR
SAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTFDSS
KDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSLAIY
TQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIK
TDMKIVPVKTLQDAIDYLKNNP

Nucleotide


Download         Length: 1509 bp        

>NTDB_id=991771 AT689_RS04190 WP_001280730.1 781312..782820(+) (sepM) [Streptococcus pneumoniae strain NCTC7465]
ATGTCAGATAAGATTGGCTTATTCACAGGCTCATTTGATCCGATGACAAATGGGCATCTGGATATCATTGAACGGGCGAG
CAGACTCTTTGATAAGCTCTATGTCGGTATTTTTTTTAATCCCCACAAACAAGGATTTCTTCCTATCGAAAATCGTAAAC
GGGGGCTAGAAAAGGCTTTGGGACATCTGGAAAATGTTGAAGTCGTGGCTTCTCATGATGAATTGGTGGTCGATGTTGCA
AAAAGATTGGGTGCTACTTGTCTAGTGCGTGGTTTGAGGAATGCGTCGGATTTGCAATATGAAGCCAGTTTTGATTACTA
CAATCATCAGCTGTCTTCTGATATAGAGACTATTTATTTACATAGTCGACCTGAACATCTCTATATCAGTTCATCAGGCG
TTAGAGAGCTTTTGAAGTTTGGTCAGGATATTGCCTGCTATGTTCCCGAGAGTATTTTGGAGGAAATAAGAAATGAAAAA
AAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCCTTATTATAT
AGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTGGTGCCTATC
AATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACAGATATTCGT
AGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAACATCACAAAA
TATGGCCAAGTATCAAGGTCTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGGGTTTATGTCTTGAATGTGA
CGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTTGATAGTTCC
AAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGGGCAAACCAA
GTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGAATTGGAATCGGCTTGATTGATCGTACAGAGGTAA
TCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTAGCTATCTAT
ACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGGTAATGTGGG
AGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTGATAACCCTG
TTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAAACAATCAAG
ACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterProScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(387-453)

PDZ domain (PDZ_2)

(287-350)

Cytidylyltransferase-like (CTP_transf_like)

(7-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

58.96

68.924

0.406