Detailed information NTG0989490

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: HMPREF9425_RS01965
• Genome accession: NZ_GL831112
• Coordinates: 371839..373944 (+)
• Length: 701 a.a.
• NCBI ID: WP_003094808.1
• Uniprot ID: A0ABP2KKP1
• Organism: Streptococcus vestibularis ATCC 49124
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 366839..378944

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS01935 (HMPREF9425_0407)	-	366852..367484 (+)	633	WP_003096283.1	nicotinate-nucleotide adenylyltransferase	-
HMPREF9425_RS01940 (HMPREF9425_0408)	yqeK	367481..368074 (+)	594	WP_003093370.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
HMPREF9425_RS01945 (HMPREF9425_0409)	-	368078..368533 (+)	456	WP_003096285.1	cysteine hydrolase family protein	-
HMPREF9425_RS01950 (HMPREF9425_0410)	rsfS	368593..368943 (+)	351	WP_003093907.1	ribosome silencing factor	-
HMPREF9425_RS01955 (HMPREF9425_0411)	-	369267..370007 (+)	741	WP_264472446.1	class I SAM-dependent DNA methyltransferase	-
HMPREF9425_RS01960 (HMPREF9425_0412)	-	370014..371105 (+)	1092	WP_003096290.1	nucleotidyltransferase	-
HMPREF9425_RS01965 (HMPREF9425_0413)	clpE	371839..373944 (+)	2106	WP_003094808.1	AAA family ATPase	Regulator
HMPREF9425_RS01970	-	374285..374863 (+)	579	WP_003094615.1	hypothetical protein	-
HMPREF9425_RS01975 (HMPREF9425_0415)	-	374882..375226 (+)	345	WP_003096294.1	hypothetical protein	-
HMPREF9425_RS01980 (HMPREF9425_0416)	-	375264..375506 (+)	243	WP_003096296.1	hypothetical protein	-
HMPREF9425_RS01985 (HMPREF9425_0417)	-	375605..376381 (+)	777	WP_003096299.1	FxLYD domain-containing protein	-
HMPREF9425_RS01990 (HMPREF9425_0418)	-	376413..376712 (-)	300	WP_003096302.1	hypothetical protein	-
HMPREF9425_RS01995 (HMPREF9425_0419)	-	376709..377128 (-)	420	WP_003096304.1	HIT family protein	-
HMPREF9425_RS02000 (HMPREF9425_0420)	pptA	377193..377924 (+)	732	WP_003096306.1	ABC transporter ATP-binding protein	Regulator

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77383.24 Da
• Isoelectric Point: 4.6745

>NTDB_id=989490 HMPREF9425_RS01965 WP_003094808.1 371839..373944(+) (clpE) [Streptococcus vestibularis ATCC 49124]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTEDLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAE

Nucleotide

• Length: 2106 bp

>NTDB_id=989490 HMPREF9425_RS01965 WP_003094808.1 371839..373944(+) (clpE) [Streptococcus vestibularis ATCC 49124]
ATGAACAACAACTTTAACAATATGGACGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATTTACCGCCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTCAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGTGAAGGTAAATTGGATCCAGTTATTGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACAAAAAATAACCCAGTCCTTGTCGGGGACGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGTTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATTATCCT
ATTCTTCGATGAAATCCACCAAATTCTTGGTGCTGGAAGCACTGGCGATGGTCAAGGATCTAAAGGTCTGGCTGATATTT
TGAAACCTGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCTGCCCTAGCTCGTCGTTTCAACGAAGTTAAGGTTAATGCTCCATCTGCTGAAGATACCTTCAAGATTCTCCAAGG
TATCCGTGACCTTTATGAAAAACACCACAATGTTATCTTACCAGATGATGTTTTGAAAGCAGCAGTAGATTTCTCTGTAC
AATATATTCCACAACGTAGCTTACCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAATGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCCAACCATACAGAAGACCTTAAAG
TCACTGCAACTGTCAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAGGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATCATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCTGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGCTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGTTACGATGAAGTCATGGGGGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTGAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

• AAA lid domain (AAA_lid_9) (257-351)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.857	99.857	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	49.088	93.866	0.461
clpE	Streptococcus pneumoniae R6	48.678	91.726	0.447
clpE	Streptococcus pneumoniae D39	48.678	91.726	0.447
clpE	Streptococcus pneumoniae Rx1	48.678	91.726	0.447
clpE	Streptococcus pneumoniae TIGR4	48.442	91.583	0.444
clpC	Bacillus subtilis subsp. subtilis str. 168	45.692	92.725	0.424
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.243	92.867	0.392
clpC	Streptococcus pneumoniae TIGR4	43.087	88.73	0.382
clpC	Streptococcus pneumoniae Rx1	43.087	88.73	0.382
clpC	Streptococcus pneumoniae D39	43.087	88.73	0.382
clpC	Streptococcus thermophilus LMD-9	42.95	88.017	0.378
clpC	Streptococcus thermophilus LMG 18311	42.811	88.302	0.378
clpC	Streptococcus mutans UA159	42.332	89.301	0.378