Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   HMPREF9319_RS08780 Genome accession   NZ_GL397128
Coordinates   1829935..1831242 (-) Length   435 a.a.
NCBI ID   WP_003066569.1    Uniprot ID   E0PG58
Organism   Streptococcus equinus ATCC 700338     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1824935..1836242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS08735 (HMPREF9319_1821) rsgA 1825202..1826074 (-) 873 WP_003066549.1 ribosome small subunit-dependent GTPase A -
  HMPREF9319_RS08750 (HMPREF9319_1822) - 1826520..1826747 (-) 228 WP_003066551.1 hypothetical protein -
  HMPREF9319_RS11215 (HMPREF9319_1823) comD/comD3 1826879..1827193 (-) 315 WP_003066552.1 GHKL domain-containing protein Regulator
  HMPREF9319_RS11220 - 1827373..1827582 (-) 210 WP_231729916.1 hypothetical protein -
  HMPREF9319_RS10840 (HMPREF9319_1826) comE/comE2 1827595..1827816 (-) 222 WP_003066558.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  HMPREF9319_RS08760 (HMPREF9319_1827) - 1827788..1828150 (-) 363 WP_003066560.1 bacteriocin immunity protein -
  HMPREF9319_RS08770 (HMPREF9319_1829) - 1828707..1829018 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  HMPREF9319_RS08775 (HMPREF9319_1830) - 1829776..1829913 (+) 138 WP_003066566.1 hypothetical protein -
  HMPREF9319_RS08780 (HMPREF9319_1831) comD/comD1 1829935..1831242 (-) 1308 WP_003066569.1 sensor histidine kinase Regulator
  HMPREF9319_RS08785 (HMPREF9319_1832) comE/comE1 1831250..1831933 (-) 684 WP_003066571.1 response regulator transcription factor Regulator
  HMPREF9319_RS08790 (HMPREF9319_1833) - 1831998..1832282 (-) 285 WP_003066573.1 LytTR family DNA-binding domain-containing protein -
  HMPREF9319_RS08800 (HMPREF9319_1835) - 1832979..1833992 (-) 1014 WP_003066577.1 hypothetical protein -
  HMPREF9319_RS08805 (HMPREF9319_1836) - 1834164..1834460 (-) 297 WP_003066579.1 bacteriocin immunity protein -
  HMPREF9319_RS08810 (HMPREF9319_1837) - 1834460..1834678 (-) 219 WP_003066580.1 Blp family class II bacteriocin -
  HMPREF9319_RS11485 - 1834871..1834990 (-) 120 WP_253066439.1 CPBP family glutamic-type intramembrane protease -
  HMPREF9319_RS11225 (HMPREF9319_1838) - 1834987..1835307 (-) 321 WP_231557401.1 CPBP family intramembrane glutamic endopeptidase -
  HMPREF9319_RS11230 (HMPREF9319_1839) - 1835364..1835543 (-) 180 WP_003066584.1 hypothetical protein -
  HMPREF9319_RS08825 (HMPREF9319_1840) - 1835714..1836025 (-) 312 WP_003066586.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 51212.82 Da        Isoelectric Point: 6.0108

>NTDB_id=989441 HMPREF9319_RS08780 WP_003066569.1 1829935..1831242(-) (comD/comD1) [Streptococcus equinus ATCC 700338]
MSDYLSELAYYPVIMLIYSNVRGEKLKLWEIVTIAVAFFVIDFTWFYTIIGRILILMFLSYLRDKTLPFSLYVFYGSIPW
VIESAFKRIISFFIIPFFNFSYTDLDKNNLLFVIVEFSIILMYFMMVQLFKINFQTFIALSEIKNLRKKLIFTDLTMMFY
YVMIEFLTGMEVYGGVPNLVYRQWLVVLYFTFFTLMLFYMNRSYQNWLEKEVSLAREQELHSLSVYSKQIEGLYEELRAF
RHDYANILASLKEGIDQNDMSMVRNIYNAVLEDSGKFIQHSRFNIGRLTNIDNDAIKSLLSAEFLEAESHHIEVELEVKD
KIGTPDIPLLDYVRLVSILCDNAIEAAIEAEKPAMIIACFYQGDDYLLIIDNTTKEERVPVELIYQKNYSSKGFGRGVGL
KTVNQMLKKYPNMSVQTSSKNYHFRQTIRIKKSFD

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=989441 HMPREF9319_RS08780 WP_003066569.1 1829935..1831242(-) (comD/comD1) [Streptococcus equinus ATCC 700338]
ATGAGTGATTATCTAAGTGAACTAGCTTACTATCCTGTGATTATGTTGATTTACTCTAATGTTAGAGGAGAAAAACTGAA
ATTGTGGGAAATAGTAACGATAGCTGTTGCTTTCTTCGTCATTGATTTTACATGGTTTTACACTATTATTGGTCGTATTT
TAATATTGATGTTTCTATCTTATTTGAGAGATAAAACCTTGCCCTTTTCTCTATACGTATTTTATGGGAGTATTCCATGG
GTTATAGAGAGTGCTTTTAAAAGAATTATTAGTTTCTTCATTATTCCATTTTTTAATTTTAGTTATACCGATTTAGATAA
AAATAATTTATTATTTGTCATTGTAGAATTTTCAATAATTCTGATGTATTTTATGATGGTGCAGTTGTTTAAAATTAACT
TTCAAACTTTTATTGCACTAAGTGAGATAAAAAATCTACGAAAGAAACTAATATTTACAGATTTAACAATGATGTTTTAC
TATGTCATGATTGAATTTTTAACAGGTATGGAAGTTTATGGTGGTGTCCCAAACTTGGTTTATCGCCAATGGTTGGTGGT
TCTCTATTTCACTTTCTTCACTTTAATGTTGTTTTATATGAATCGCTCTTATCAAAATTGGCTGGAGAAAGAAGTATCGT
TAGCGCGGGAGCAAGAACTGCATTCTTTGTCGGTATATAGCAAGCAAATCGAAGGCTTATATGAGGAACTAAGAGCTTTT
CGTCATGATTATGCTAATATCTTAGCGAGTTTAAAAGAGGGAATCGACCAAAATGATATGAGTATGGTGAGGAATATTTA
TAATGCCGTTTTAGAGGATTCTGGAAAGTTTATTCAGCATAGTCGCTTCAATATTGGACGATTGACTAATATTGATAATG
ATGCGATAAAAAGCCTTTTATCAGCTGAATTTTTAGAAGCGGAATCTCATCATATTGAGGTAGAATTAGAAGTTAAAGAT
AAAATTGGAACTCCAGATATTCCTTTGTTAGATTATGTGCGGCTCGTCTCCATTTTATGTGACAATGCGATTGAAGCGGC
TATTGAAGCTGAAAAGCCTGCCATGATTATTGCTTGTTTCTATCAAGGGGATGACTATTTACTAATTATAGATAACACCA
CAAAAGAAGAGCGAGTTCCTGTGGAATTGATTTACCAGAAGAATTATTCAAGTAAGGGCTTTGGACGAGGTGTTGGTCTT
AAAACGGTTAACCAGATGTTGAAAAAGTATCCAAATATGTCGGTACAAACATCAAGCAAGAATTATCATTTCAGACAAAC
AATACGAATCAAAAAATCATTCGACTGA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(330-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PG58

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

76.724

53.333

0.409