Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   F7686_RS01740 Genome accession   NZ_FNFT01000001
Coordinates   329213..330973 (-) Length   586 a.a.
NCBI ID   WP_066956561.1    Uniprot ID   A0A1G8XCC3
Organism   Methanoculleus thermophilus strain DSM 2373     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 324213..335973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7686_RS01720 (SAMN04488571_101353) - 324755..325858 (-) 1104 WP_083524777.1 FecCD family ABC transporter permease -
  F7686_RS01725 (SAMN04488571_101354) - 325855..326964 (-) 1110 WP_066956553.1 ABC transporter substrate-binding protein -
  F7686_RS01730 (SAMN04488571_101355) - 327194..328060 (+) 867 WP_066956555.1 S16 family serine protease -
  F7686_RS01735 (SAMN04488571_101356) - 328235..328822 (+) 588 WP_150468680.1 PsbP-related protein -
  F7686_RS01740 (SAMN04488571_101357) hexB 329213..330973 (-) 1761 WP_066956561.1 DNA mismatch repair endonuclease MutL Machinery gene
  F7686_RS01745 (SAMN04488571_101358) mutS 330970..333594 (-) 2625 WP_066956564.1 DNA mismatch repair protein MutS -
  F7686_RS01750 (SAMN04488571_101359) - 333738..334991 (+) 1254 WP_066956569.1 3-isopropylmalate dehydratase large subunit -
  F7686_RS01755 (SAMN04488571_101360) - 334995..335486 (+) 492 WP_066956573.1 3-isopropylmalate dehydratase small subunit -

Sequence

Protein


Download         Length: 586 a.a.        Molecular weight: 63031.99 Da        Isoelectric Point: 5.7448

>NTDB_id=989350 F7686_RS01740 WP_066956561.1 329213..330973(-) (hexB) [Methanoculleus thermophilus strain DSM 2373]
MTKIRVLDPDTVNQIAAGEVVERPASVVKELIENAIDAGSTSILIEITSDMAAVTKIRVTDDGEGMTPEEAVLAFAPHAT
SKIRDIADLSTLRTLGFRGEALASIAAVAEVTLVTRPRGSGALAGTRLVIRGGEIVEKSEVGAPEGTTIIVEHLFYNTPA
RRKFLKSRNTELAHIYAAVENLALAHGEVAFRVVQNGKERLSTQRSRDLLATITGLYGADLARALVPVEGRLPILTIRGY
VSRPSENRGNQSEIYISINGRSISSRQIAAAVREGYGTLLPKDRYPVAFLDLTIETDLVDVNVHPTKREVRLSREREITG
AIATAVGEALAGHDLLGDAPAEPVQQPLLPQEPVPAPAPAAGEPEAAYTARHRELALSDRQLRRTETEAGGQENLLPPME
PIGQVAATYIVAEGTDGTLYLVDQHAAHERILYDQVVEQRDKAAGSQELIMPVVLSLPPKESAALRDAVPLLAGEGFVVE
EFGRDTFAVRAVPAALGAVEDPASIREMIAEFLAGEARAAPDRREAVTCIIACRGAVKAGALLTAEQQKRLLMQLARTKT
PWTCPHGRPTVVAFDKRKLDGLFRRG

Nucleotide


Download         Length: 1761 bp        

>NTDB_id=989350 F7686_RS01740 WP_066956561.1 329213..330973(-) (hexB) [Methanoculleus thermophilus strain DSM 2373]
ATGACGAAGATCCGGGTCCTCGACCCCGACACCGTGAACCAGATCGCCGCCGGCGAGGTCGTGGAGCGGCCGGCATCGGT
GGTGAAAGAACTCATCGAGAACGCGATCGATGCCGGTTCGACGAGCATCCTCATCGAGATTACGTCGGACATGGCTGCTG
TCACGAAGATCCGGGTGACCGACGACGGCGAGGGGATGACGCCGGAGGAGGCCGTCCTTGCGTTTGCGCCCCACGCCACG
AGCAAGATCCGAGATATCGCCGATCTTTCGACCCTCCGGACGCTGGGGTTCCGGGGGGAGGCGCTCGCGAGCATCGCCGC
CGTCGCGGAGGTGACCCTGGTCACCCGTCCCCGTGGGAGCGGCGCGCTCGCCGGGACACGGCTGGTGATCAGGGGCGGTG
AGATCGTCGAGAAGAGCGAGGTGGGCGCCCCGGAGGGGACGACGATCATCGTGGAGCACCTCTTCTACAACACCCCCGCC
CGCCGGAAGTTCCTAAAGAGCAGGAACACTGAACTTGCCCACATCTACGCCGCTGTGGAGAACCTGGCCCTCGCCCACGG
TGAGGTTGCCTTCCGGGTGGTGCAGAACGGAAAGGAGCGGCTCTCGACCCAGCGGTCCAGGGACCTTCTTGCCACCATCA
CCGGACTTTACGGTGCAGACCTTGCCCGGGCGCTCGTCCCGGTCGAGGGAAGGCTCCCGATCCTTACCATCCGCGGCTAT
GTCTCCCGCCCGTCGGAGAACCGGGGAAACCAATCTGAGATCTATATCAGCATCAACGGCCGGAGCATCTCCTCCCGCCA
GATCGCCGCCGCCGTCCGGGAGGGCTACGGCACCCTCCTCCCAAAGGACCGTTATCCTGTGGCATTCCTCGATCTCACGA
TCGAGACCGATCTTGTGGACGTCAACGTCCACCCGACAAAGAGGGAGGTCCGCCTATCCCGGGAGCGGGAGATCACGGGA
GCAATTGCAACCGCGGTAGGAGAGGCCCTCGCCGGGCACGACCTTCTTGGCGATGCTCCGGCCGAACCGGTGCAGCAGCC
GCTCCTGCCGCAAGAACCTGTCCCGGCTCCCGCTCCAGCGGCAGGCGAGCCCGAAGCGGCTTACACGGCCCGGCACCGGG
AACTCGCCCTCTCGGATCGTCAGCTCCGCCGGACGGAGACAGAGGCAGGTGGACAGGAGAACCTCCTCCCCCCGATGGAG
CCGATAGGACAGGTAGCCGCGACCTACATCGTGGCGGAGGGGACCGACGGCACCCTCTACCTCGTCGACCAGCATGCGGC
CCATGAGCGGATCCTCTACGACCAGGTCGTGGAACAGCGCGACAAGGCGGCCGGGTCGCAGGAGTTGATCATGCCCGTCG
TCCTCTCCCTTCCACCGAAAGAGTCGGCCGCGCTCCGGGACGCGGTGCCTCTCCTCGCGGGCGAGGGATTTGTGGTGGAG
GAGTTCGGCCGGGATACCTTCGCCGTCCGGGCGGTGCCGGCCGCCCTCGGGGCCGTCGAGGACCCCGCAAGCATCAGGGA
GATGATAGCCGAGTTCCTCGCCGGGGAGGCCCGGGCCGCTCCCGACCGGCGTGAGGCGGTCACCTGCATCATCGCATGCC
GCGGTGCTGTGAAGGCCGGCGCCCTCCTCACCGCCGAGCAGCAGAAGCGCCTCCTTATGCAACTTGCCCGGACCAAAACC
CCCTGGACCTGCCCGCACGGAAGGCCGACGGTCGTGGCGTTCGACAAGCGCAAACTCGACGGACTCTTCCGGCGGGGATA
A

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(214-330)

MutL C terminal dimerisation domain (MutL_C)

(402-541)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1G8XCC3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

37.014

100

0.406

Multiple sequence alignment