Detailed information NTG0098920

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R8570_RS09370
• Genome accession: NZ_AP026932
• Coordinates: 1848520..1849557 (-)
• Length: 345 a.a.
• NCBI ID: WP_050263715.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701549
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1843520..1854557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8570_RS09345 (PC1528_18560)	-	1844259..1845590 (-)	1332	WP_000390039.1	hemolysin family protein	-
R8570_RS09350 (PC1528_18570)	endA	1845881..1846705 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
R8570_RS09355 (PC1528_18580)	-	1846744..1846932 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
R8570_RS09360 (PC1528_18590)	murA	1846925..1848208 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R8570_RS09365 (PC1528_18600)	-	1848232..1848462 (-)	231	WP_000250392.1	DUF1146 family protein	-
R8570_RS09370 (PC1528_18610)	sepM	1848520..1849557 (-)	1038	WP_050263715.1	SepM family pheromone-processing serine protease	Regulator
R8570_RS09375 (PC1528_18620)	coaD	1849541..1850029 (-)	489	WP_044813415.1	pantetheine-phosphate adenylyltransferase	-
R8570_RS09380 (PC1528_18630)	rsmD	1850019..1850558 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R8570_RS09385 (PC1528_18640)	asnA	1850623..1851615 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R8570_RS09390 (PC1528_18650)	-	1851726..1852409 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R8570_RS09395 (PC1528_18660)	-	1852465..1853205 (-)	741	WP_000152678.1	RNA methyltransferase	-
R8570_RS09400 (PC1528_18670)	-	1853239..1853517 (+)	279	WP_001174613.1	acylphosphatase	-
R8570_RS09405 (PC1528_18680)	yidC	1853595..1854521 (+)	927	WP_050263714.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37509.56 Da
• Isoelectric Point: 5.2280

>NTDB_id=98920 R8570_RS09370 WP_050263715.1 1848520..1849557(-) (sepM) [Streptococcus pneumoniae strain PZ900701549]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGNSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNSP

Nucleotide

• Length: 1038 bp

>NTDB_id=98920 R8570_RS09370 WP_050263715.1 1848520..1849557(-) (sepM) [Streptococcus pneumoniae strain PZ900701549]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGAATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAGTCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60	98.551	0.591