Detailed information NTG0989173

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: AAFQ93_RS05160
• Genome accession: NZ_CP152419
• Coordinates: 1077919..1080171 (-)
• Length: 750 a.a.
• NCBI ID: WP_375554855.1
• Uniprot ID: -
• Organism: Streptococcus nidrosiense strain SO-23-1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1072919..1085171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAFQ93_RS05135 (AAFQ93_05125)	-	1073996..1074694 (+)	699	WP_153225419.1	GntR family transcriptional regulator	-
AAFQ93_RS05140 (AAFQ93_05130)	metK	1074933..1076123 (+)	1191	WP_195184351.1	methionine adenosyltransferase	-
AAFQ93_RS05145 (AAFQ93_05135)	-	1076158..1076790 (-)	633	WP_375554854.1	GNAT family N-acetyltransferase	-
AAFQ93_RS05150 (AAFQ93_05140)	-	1077018..1077317 (-)	300	WP_153225417.1	DUF1827 family protein	-
AAFQ93_RS05155 (AAFQ93_05145)	-	1077381..1077830 (-)	450	WP_045762885.1	NUDIX hydrolase	-
AAFQ93_RS05160 (AAFQ93_05150)	clpE	1077919..1080171 (-)	2253	WP_375554855.1	AAA family ATPase	Regulator
AAFQ93_RS05165 (AAFQ93_05155)	-	1080568..1080798 (-)	231	WP_000443576.1	DUF1797 family protein	-
AAFQ93_RS05170 (AAFQ93_05160)	-	1080994..1081677 (+)	684	WP_223140764.1	amino acid ABC transporter permease	-
AAFQ93_RS05175 (AAFQ93_05165)	-	1081677..1082411 (+)	735	WP_223140765.1	amino acid ABC transporter ATP-binding protein	-
AAFQ93_RS05180 (AAFQ93_05170)	-	1082550..1083404 (+)	855	WP_000192098.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-

Sequence

Protein

• Length: 750 a.a.
• Molecular weight: 83605.80 Da
• Isoelectric Point: 4.9771

>NTDB_id=989173 AAFQ93_RS05160 WP_375554855.1 1077919..1080171(-) (clpE) [Streptococcus nidrosiense strain SO-23-1]
MLCQNCKINDSTIHLYTNLNGQQKQIDLCQNCYKIIKTDPNNSLFKGITDLNNRDFDPFGDFFNDLNNFRPSSNNNNIPP
TQSGGGYGGNGGYGSQNRGPAQTPPPIQEKGLLDEYGINVTEIARRGNIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIREREDVILFIDEIHEIVGAGSA
GEGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGIQKKYEDYHHVHYTDGA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEM
QKTKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLINLADDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGATREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKENLLQIVDLMLDDVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
SEKNLKAVMTSNGKIMIKSKNKLETVDSND

Nucleotide

• Length: 2253 bp

>NTDB_id=989173 AAFQ93_RS05160 WP_375554855.1 1077919..1080171(-) (clpE) [Streptococcus nidrosiense strain SO-23-1]
ATGCTCTGTCAAAACTGTAAAATCAATGACTCAACGATTCATCTTTATACCAATCTCAATGGGCAACAAAAGCAAATCGA
CCTTTGTCAAAATTGCTACAAAATTATCAAAACAGATCCTAACAATAGCTTATTCAAGGGCATTACAGATTTAAACAACC
GTGATTTTGATCCCTTTGGAGACTTCTTTAACGATCTCAACAACTTTAGACCTTCTTCTAATAACAACAATATCCCCCCA
ACTCAGTCAGGGGGTGGATACGGTGGAAATGGTGGCTATGGTTCCCAAAATCGTGGTCCTGCCCAAACCCCACCACCAAT
CCAGGAAAAAGGACTCTTGGATGAATATGGTATCAATGTCACTGAGATTGCCCGTCGTGGAAATATTGACCCTGTAATTG
GCCGCGACGAAGAGATAATCCGTGTCATTGAAATCCTCAACCGCAGAACAAAAAACAACCCTGTCCTCATCGGTGAGCCC
GGTGTTGGTAAGACAGCTGTTGTCGAAGGTTTAGCTCAGAAAATTGTTGACGGTGATGTTCCGCATAAGCTTCAAGGTAA
GGAAGTCATCCGCTTAGATGTCGTTAGCCTTGTTCAAGGAACAGGTATCCGAGGTCAGTTTGAAGAGCGCATGCAAAAAC
TCATGGAAGAAATTCGTGAGCGCGAGGATGTTATTCTCTTCATTGACGAAATTCATGAAATTGTCGGTGCTGGTTCAGCA
GGAGAAGGGAATATGGATGCAGGAAATATCCTAAAACCAGCTCTTGCTCGTGGCGAACTCCAACTGGTTGGTGCTACTAC
CCTCAATGAATATCGCATCATCGAAAAAGATGCTGCCCTTGAACGTCGTATGCAACCTGTCAAAGTTGATGAACCAACTG
TGGAAGAAACCATTATTATCCTGAAAGGTATCCAAAAGAAATACGAAGATTACCACCACGTTCATTATACTGACGGCGCT
ATCGAAGCGGCCGCTACCCTTTCTAACCGCTACATCCAAGATCGTTTCTTGCCAGACAAGGCCATTGACCTTCTAGATGA
AGCTGGTTCAAAAATGAACTTAACCTTGAATTTTGTAGATCCTAAAGTCATCGACCAACGCTTAATCGAAGCAGAAAATC
TGAAGGCACAAGCAACCCGCGATGAAGATTTTGAAAAAGCAGCCTACTTCCGTGACCAGATTGCCAAATATAAGGAAATG
CAAAAGACAAAGGTAACGGATCAGGATACCCCAATCATCAGCGAAAAGACGATTGAACACATCATCGAACAAAAGACTAA
TATCCCAGTTGGTGACCTTAAGGAAAAAGAACAGTCTCAACTCATCAACCTAGCAGATGACCTCAAGGCTCATGTTATTG
GTCAAGATGATGCAGTTGATAAAATCGCTAAGGCTATCCGTCGTAACCGTGTTGGACTCGGTACTCCAAACCGTCCAATC
GGTAGCTTCCTCTTTGTTGGTCCTACTGGTGTCGGTAAAACAGAACTTTCTAAACAACTAGCTATCGAACTCTTTGGCTC
TGCTGACAGCATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGTGTGGCTAAACTCGTCGGTGCCCCTCCAG
GATACGTAGGCTATGATGAAGCAGGTCAATTGACTGAAAAAGTTCGTCGTAACCCCTACTCACTGATCCTCTTGGATGAA
GTTGAAAAAGCCCATCCAGATGTTATGCATATGTTCCTTCAAGTCTTGGATGATGGTCGTTTAACGGATGGGCAAGGTCG
TACTGTTAGCTTTAAAGACGCCATCATTATCATGACCTCAAATGCAGGTACAGGTAAGGCAGAAGCTAGTGTTGGATTTG
GTGCTACTCGTGAAGGCCGTACCAACTCAGTCCTTGGAGAATTAGGCAACTTCTTTAGCCCCGAATTCATGAACCGTTTT
GATGGTATTATCGAATTCAAGGCTCTCAGCAAGGAAAATCTCCTTCAAATCGTTGATCTCATGTTAGATGATGTCAATAA
ACGACTCTCAAGCAATAACATCCATTTGGATGTAACAGATAAGGTTAAAGAAAAACTTGTAGACCTTGGTTATGATCCAA
AAATGGGAGCTCGTCCACTCCGTCGTACCATCCAAGACTACATCGAAGATGCAATCACGGACTATTACCTTGAAAATCCA
AGTGAGAAAAACCTCAAGGCTGTCATGACTAGCAATGGTAAAATCATGATTAAATCAAAAAATAAATTGGAAACAGTTGA
CTCAAATGACTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (478-641)

• ATPase family associated with various cellular activities (AAA) (AAA) (155-273)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (649-724)

• AAA lid domain (AAA_lid_9) (293-390)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	93.984	99.733	0.937
clpE	Streptococcus pneumoniae D39	93.984	99.733	0.937
clpE	Streptococcus pneumoniae R6	93.984	99.733	0.937
clpE	Streptococcus pneumoniae TIGR4	93.85	99.733	0.936
clpE	Streptococcus mutans UA159	83.845	99.867	0.837
clpC	Lactococcus lactis subsp. cremoris KW2	76.09	100	0.768
clpC	Bacillus subtilis subsp. subtilis str. 168	50.789	92.933	0.472
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.531	86.4	0.411
clpC	Streptococcus pneumoniae TIGR4	47.293	83.733	0.396
clpC	Streptococcus pneumoniae Rx1	47.293	83.733	0.396
clpC	Streptococcus pneumoniae D39	47.293	83.733	0.396
clpC	Streptococcus thermophilus LMD-9	46.955	83.2	0.391
clpC	Streptococcus thermophilus LMG 18311	46.635	83.2	0.388
clpC	Streptococcus mutans UA159	45.92	83.333	0.383