Detailed information NTG0988963

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SLO00_RS10325
• Genome accession: NZ_CP152409
• Coordinates: 2061113..2062156 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN53
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2056113..2067156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SLO00_RS10295 (SLO00_010300)	-	2056531..2057787 (-)	1257	WP_001795438.1	aminopeptidase	-
SLO00_RS10300 (SLO00_010305)	-	2057790..2057990 (-)	201	WP_000180461.1	DUF1128 family protein	-
SLO00_RS10305 (SLO00_010310)	-	2058137..2058601 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SLO00_RS10310 (SLO00_010315)	-	2058608..2058883 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SLO00_RS10315 (SLO00_010320)	-	2059161..2060378 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SLO00_RS10320 (SLO00_010325)	vraR	2060494..2061123 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
SLO00_RS10325 (SLO00_010330)	vraS	2061113..2062156 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SLO00_RS10330 (SLO00_010335)	liaF	2062153..2062854 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SLO00_RS10335 (SLO00_010340)	-	2062869..2063255 (-)	387	WP_001110179.1	hypothetical protein	-
SLO00_RS10340 (SLO00_010345)	map	2063472..2064230 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SLO00_RS10345 (SLO00_010350)	-	2064758..2065744 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SLO00_RS10350 (SLO00_010355)	-	2066234..2066647 (-)	414	WP_001549145.1	hypothetical protein	-
SLO00_RS10355 (SLO00_010360)	-	2066676..2066786 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=988963 SLO00_RS10325 WP_001017131.1 2061113..2062156(-) (vraS) [Staphylococcus aureus strain BSN53]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=988963 SLO00_RS10325 WP_001017131.1 2061113..2062156(-) (vraS) [Staphylococcus aureus strain BSN53]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1