Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R8624_RS08875 Genome accession   NZ_AP026930
Coordinates   1726750..1727370 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain PZ900701208     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1721750..1732370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8624_RS08850 (PC1195_17320) recA 1722127..1723293 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R8624_RS08855 (PC1195_17330) cinA 1723348..1724604 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  R8624_RS08860 (PC1195_17340) brpA 1724689..1725705 (-) 1017 WP_000239284.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8624_RS08865 (PC1195_17350) - 1725713..1726231 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R8624_RS08870 (PC1195_17360) tsaE 1726221..1726664 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8624_RS08875 (PC1195_17370) comM 1726750..1727370 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R8624_RS08880 (PC1195_17380) - 1727753..1728616 (-) 864 WP_001093628.1 helix-turn-helix domain-containing protein -
  R8624_RS08885 (PC1195_17390) - 1728974..1729927 (+) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -
  R8624_RS08890 (PC1195_17400) - 1730051..1730220 (+) 170 Protein_1741 PhrA family quorum-sensing system peptide -
  R8624_RS08895 (PC1195_17410) - 1730535..1730831 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=98766 R8624_RS08875 WP_000839908.1 1726750..1727370(-) (comM) [Streptococcus pneumoniae strain PZ900701208]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=98766 R8624_RS08875 WP_000839908.1 1726750..1727370(-) (comM) [Streptococcus pneumoniae strain PZ900701208]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment