Detailed information NTG0987421

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SL323_RS14345
• Genome accession: NZ_CP152120
• Coordinates: 2821334..2822221 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN62-2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2816334..2827221

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SL323_RS14315 (SL323_14320)	-	2816353..2816445 (+)	93	WP_010956583.1	hypothetical protein	-
SL323_RS14320 (SL323_14325)	-	2816553..2817050 (-)	498	WP_001065268.1	glutathione peroxidase	-
SL323_RS14325 (SL323_14330)	-	2817060..2817320 (-)	261	WP_001789910.1	hypothetical protein	-
SL323_RS14330 (SL323_14335)	-	2817702..2817815 (-)	114	WP_001791776.1	hypothetical protein	-
SL323_RS14335 (SL323_14340)	-	2818474..2820474 (-)	2001	WP_000776751.1	ABC transporter permease	-
SL323_RS14340 (SL323_14345)	-	2820471..2821226 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SL323_RS14345 (SL323_14350)	braS	2821334..2822221 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SL323_RS14350 (SL323_14355)	braR	2822232..2822897 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SL323_RS14355 (SL323_14360)	-	2822923..2823123 (-)	201	WP_000604728.1	hypothetical protein	-
SL323_RS14360 (SL323_14365)	-	2823321..2824745 (+)	1425	WP_000953744.1	alkaline phosphatase	-
SL323_RS14365 (SL323_14370)	-	2824815..2824925 (+)	111	WP_001791296.1	hypothetical protein	-
SL323_RS14370 (SL323_14375)	-	2825028..2825483 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SL323_RS14375 (SL323_14380)	-	2825728..2826489 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=987421 SL323_RS14345 WP_000143419.1 2821334..2822221(-) (braS) [Staphylococcus aureus strain BSN62-2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=987421 SL323_RS14345 WP_000143419.1 2821334..2822221(-) (braS) [Staphylococcus aureus strain BSN62-2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997