Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | AAF758_RS09175 | Genome accession | NZ_CP152119 |
| Coordinates | 1878723..1881176 (-) | Length | 817 a.a. |
| NCBI ID | WP_014636516.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain Ss2301 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1874825..1918053 | 1878723..1881176 | within | 0 |
Gene organization within MGE regions
Location: 1874825..1918053
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AAF758_RS09155 (AAF758_09155) | dusB | 1874825..1875829 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| AAF758_RS09160 (AAF758_09160) | - | 1875975..1876748 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| AAF758_RS09165 (AAF758_09165) | pnuC | 1876741..1877562 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| AAF758_RS09170 (AAF758_09170) | - | 1877572..1878609 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| AAF758_RS09175 (AAF758_09175) | clpC | 1878723..1881176 (-) | 2454 | WP_014636516.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| AAF758_RS09180 (AAF758_09180) | - | 1881182..1881640 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| AAF758_RS09185 (AAF758_09185) | - | 1881790..1882128 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| AAF758_RS09190 (AAF758_09190) | - | 1882128..1882829 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| AAF758_RS09195 (AAF758_09195) | tsf | 1883092..1884132 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| AAF758_RS09200 (AAF758_09200) | rpsB | 1884288..1885064 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| AAF758_RS09205 (AAF758_09205) | - | 1885411..1885923 (-) | 513 | WP_012775452.1 | adenylate kinase | - |
| AAF758_RS09215 (AAF758_09215) | - | 1886577..1891655 (-) | 5079 | WP_238708114.1 | S8 family serine peptidase | - |
| AAF758_RS09220 (AAF758_09220) | nusG | 1891800..1892339 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| AAF758_RS09225 (AAF758_09225) | secE | 1892449..1892625 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| AAF758_RS09230 (AAF758_09230) | rpmG | 1892635..1892787 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| AAF758_RS09235 (AAF758_09235) | pbp2a | 1892821..1895034 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| AAF758_RS09240 (AAF758_09240) | - | 1895187..1896155 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| AAF758_RS09245 (AAF758_09245) | - | 1896157..1897023 (+) | 867 | WP_342593770.1 | RluA family pseudouridine synthase | - |
| AAF758_RS09250 (AAF758_09250) | purR | 1897050..1897862 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| AAF758_RS09255 (AAF758_09255) | - | 1897964..1898830 (-) | 867 | WP_012027872.1 | phosphotransferase | - |
| AAF758_RS09260 (AAF758_09260) | - | 1898830..1899771 (-) | 942 | WP_012775359.1 | 3'-5' exoribonuclease YhaM family protein | - |
| AAF758_RS09265 (AAF758_09265) | rmuC | 1899761..1900999 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| AAF758_RS09270 (AAF758_09270) | - | 1901000..1901632 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| AAF758_RS09275 (AAF758_09275) | rpe | 1901625..1902284 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| AAF758_RS09280 (AAF758_09280) | rsgA | 1902299..1903174 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| AAF758_RS09290 (AAF758_09290) | - | 1904071..1905648 (-) | 1578 | WP_012027878.1 | ABC transporter ATP-binding protein | - |
| AAF758_RS09295 (AAF758_09295) | - | 1905645..1906886 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| AAF758_RS09300 (AAF758_09300) | - | 1907255..1908118 (-) | 864 | WP_012027880.1 | Rgg/GadR/MutR family transcriptional regulator | - |
| AAF758_RS09305 (AAF758_09305) | - | 1908608..1911052 (-) | 2445 | WP_012027881.1 | alkaline phosphatase family protein | - |
| AAF758_RS09310 (AAF758_09310) | - | 1911065..1912795 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| AAF758_RS09315 (AAF758_09315) | rsmA | 1913160..1914032 (-) | 873 | WP_342593771.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| AAF758_RS09320 (AAF758_09320) | - | 1914052..1914582 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| AAF758_RS09325 (AAF758_09325) | - | 1914596..1914853 (-) | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
| AAF758_RS09330 (AAF758_09330) | - | 1914855..1915115 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| AAF758_RS09335 (AAF758_09335) | - | 1915191..1915646 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| AAF758_RS09340 (AAF758_09340) | - | 1915653..1915982 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| AAF758_RS09345 (AAF758_09345) | - | 1915972..1916259 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| AAF758_RS09350 (AAF758_09350) | - | 1916357..1916725 (-) | 369 | WP_012775453.1 | hypothetical protein | - |
| AAF758_RS09355 (AAF758_09355) | rnmV | 1916718..1917287 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| AAF758_RS09360 (AAF758_09360) | - | 1917271..1918053 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90162.56 Da Isoelectric Point: 6.3138
>NTDB_id=987376 AAF758_RS09175 WP_014636516.1 1878723..1881176(-) (clpC) [Streptococcus suis strain Ss2301]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFATSRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFATSRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=987376 AAF758_RS09175 WP_014636516.1 1878723..1881176(-) (clpC) [Streptococcus suis strain Ss2301]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGACTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGACTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus pneumoniae Rx1 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus pneumoniae D39 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus mutans UA159 |
66.049 |
99.143 |
0.655 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.706 |
99.878 |
0.646 |
| clpC | Streptococcus thermophilus LMD-9 |
64.583 |
99.878 |
0.645 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.206 |
100 |
0.493 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.526 |
99.51 |
0.443 |