Detailed information NTG0986975

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACOCJA_RS11175
• Genome accession: NZ_CP184565
• Coordinates: 2261555..2263663 (-)
• Length: 702 a.a.
• NCBI ID: WP_001058986.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain CBTW2018043
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2256555..2268663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJA_RS11160 (ACOCJA_11160)	-	2259072..2259299 (+)	228	WP_000932073.1	FeoA family protein	-
ACOCJA_RS11165 (ACOCJA_11165)	feoB	2259311..2261305 (+)	1995	WP_000432889.1	ferrous iron transport protein B	-
ACOCJA_RS11170 (ACOCJA_11170)	-	2261318..2261488 (+)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
ACOCJA_RS11175 (ACOCJA_11175)	clpE	2261555..2263663 (-)	2109	WP_001058986.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
ACOCJA_RS11180 (ACOCJA_11180)	-	2264072..2264593 (+)	522	WP_000384652.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
ACOCJA_RS11185 (ACOCJA_11185)	-	2264764..2265930 (-)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
ACOCJA_RS11190 (ACOCJA_11190)	-	2266185..2267465 (+)	1281	WP_001191004.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACOCJA_RS11195 (ACOCJA_11195)	-	2267605..2268036 (-)	432	WP_000875614.1	CHAP domain-containing protein	-
ACOCJA_RS11200 (ACOCJA_11200)	-	2268424..2268642 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77981.38 Da
• Isoelectric Point: 4.6056

>NTDB_id=986975 ACOCJA_RS11175 WP_001058986.1 2261555..2263663(-) (clpE) [Staphylococcus aureus strain CBTW2018043]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=986975 ACOCJA_RS11175 WP_001058986.1 2261555..2263663(-) (clpE) [Staphylococcus aureus strain CBTW2018043]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGCCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGGAATGTACCTGCAGCCATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTCAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGCGCTGGGTTTGATGACGGCAACCGTCCAATTGGTAGTTTCC
TATTTGTCGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTTATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTATTACTACAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGCAATGACACTGAAGAAAAAGACATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.834	91.595	0.447
clpE	Streptococcus pneumoniae Rx1	48.298	87.892	0.424
clpE	Streptococcus pneumoniae D39	48.298	87.892	0.424
clpE	Streptococcus pneumoniae R6	48.298	87.892	0.424
clpE	Streptococcus pneumoniae TIGR4	48.298	87.892	0.424
clpC	Lactococcus lactis subsp. cremoris KW2	46.519	90.028	0.419
clpC	Bacillus subtilis subsp. subtilis str. 168	44.564	93.02	0.415
clpC	Streptococcus thermophilus LMD-9	44.234	90.171	0.399
clpC	Streptococcus thermophilus LMG 18311	43.918	90.171	0.396
clpC	Streptococcus pneumoniae TIGR4	43.851	88.034	0.386
clpC	Streptococcus pneumoniae Rx1	43.851	88.034	0.386
clpC	Streptococcus pneumoniae D39	43.851	88.034	0.386
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.45	0.382