Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   MHB67_RS06490 Genome accession   NZ_CP152051
Coordinates   1318784..1320886 (-) Length   700 a.a.
NCBI ID   WP_133743886.1    Uniprot ID   -
Organism   Bacillus sp. FSL H8-0516     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1313784..1325886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MHB67_RS06465 (MHB67_06465) - 1314201..1314443 (+) 243 WP_024424676.1 aspartyl-phosphate phosphatase Spo0E family protein -
  MHB67_RS06470 (MHB67_06470) - 1314490..1315995 (-) 1506 WP_024424677.1 ATP-binding protein -
  MHB67_RS06475 (MHB67_06475) - 1316200..1316655 (+) 456 WP_024424678.1 MarR family transcriptional regulator -
  MHB67_RS06480 (MHB67_06480) motB 1316848..1317618 (-) 771 WP_024424679.1 flagellar motor protein MotB -
  MHB67_RS06485 (MHB67_06485) motA 1317611..1318405 (-) 795 WP_024424680.1 flagellar motor stator protein MotA -
  MHB67_RS06490 (MHB67_06490) clpC 1318784..1320886 (-) 2103 WP_133743886.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  MHB67_RS06495 (MHB67_06495) - 1321131..1322174 (+) 1044 WP_073204958.1 hypothetical protein -
  MHB67_RS06500 (MHB67_06500) queC 1322449..1323105 (+) 657 WP_024424683.1 7-cyano-7-deazaguanine synthase QueC -
  MHB67_RS06505 (MHB67_06505) queD 1323106..1323546 (+) 441 WP_024424684.1 6-carboxytetrahydropterin synthase QueD -
  MHB67_RS06510 (MHB67_06510) queE 1323539..1324270 (+) 732 WP_034623358.1 7-carboxy-7-deazaguanine synthase QueE -
  MHB67_RS06515 (MHB67_06515) queF 1324286..1324783 (+) 498 WP_024426839.1 preQ(1) synthase -
  MHB67_RS06520 (MHB67_06520) - 1325238..1325600 (-) 363 WP_034623357.1 winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 700 a.a.        Molecular weight: 78010.60 Da        Isoelectric Point: 4.9961

>NTDB_id=986917 MHB67_RS06490 WP_133743886.1 1318784..1320886(-) (clpC) [Bacillus sp. FSL H8-0516]
MRCQHCQVNEATIRLNMQVNSSRSQMVLCEDCYTSLMEQSKMKMGPQLFGGSSFFSQAAGHAPNMEQPKQKGLLDELGRN
LTDGANAGLIDPVIGRDEEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIASGDVPNKLKNKQIYLLDVSSLVA
NTGIRGQFEERMKQLIKELQSRKNIILFVDEIHLLVGAGSAEGSMDAGNILKPALARGELQLVGATTLKEYRQIEKDAAL
ERRFQPVIVDEPTQDEAIDILKGIQDKYEAYHGVTYSDEAIKACVQLSSRYIQDRHLPDKAIDLMDEAGSKANLSIDAAS
EDELTNRLTEIAAEKQAALKEEQYEKAAKLRDEEEAIEARLQNKTTEKEHIVTAEDIQAIVEQKTGIPVGKLQADEQTKM
KEIDVRLKARVIGQEHAVDKVAKAVKRSRAGLKSKHRPTGSFLFVGPTGVGKTELSKTLAEELFGSRDAIIRLDMSEYME
KHSVSKLIGSPPGYVGHDEAGQLTEKVRRKPYSIILLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGTADKTVKVGFQSDQEEAFEEQSLIDSLSSYFKPEFLNRFDSIIQFDSLDREDLVKIVDLLLNELSEQLKEQNLTVHVT
NEAKEKIAELGYHPAFGARPLRRTIQEHVEDQMTEILLEEEQLSGFTVDVEHDEIVVKKG

Nucleotide


Download         Length: 2103 bp        

>NTDB_id=986917 MHB67_RS06490 WP_133743886.1 1318784..1320886(-) (clpC) [Bacillus sp. FSL H8-0516]
ATGCGTTGTCAACATTGTCAAGTAAATGAAGCAACTATTCGCCTGAATATGCAAGTAAATTCGTCCCGGAGCCAAATGGT
TTTATGTGAAGACTGCTATACCTCTTTGATGGAGCAGTCAAAAATGAAAATGGGACCTCAGCTCTTTGGAGGAAGTTCAT
TCTTCTCTCAGGCAGCAGGTCATGCCCCAAACATGGAGCAGCCAAAGCAAAAAGGCTTACTCGATGAGCTCGGCCGTAAC
TTAACAGATGGAGCAAATGCTGGTTTAATTGATCCAGTCATTGGCCGTGATGAAGAAGTCGCAAGAGTCATTGAGATTTT
AAATAGAAGAAATAAAAATAACCCTGTTCTTATTGGTGAACCAGGCGTTGGGAAAACAGCGATCGCAGAAGGACTCGCGC
TCAAAATTGCGAGCGGCGATGTGCCAAATAAATTAAAGAACAAACAAATCTATTTATTAGATGTCTCCTCACTTGTCGCA
AACACAGGGATACGCGGTCAATTTGAGGAAAGAATGAAGCAGTTAATCAAAGAACTGCAAAGCCGTAAAAATATCATCTT
ATTTGTAGATGAAATCCACCTTCTTGTGGGCGCAGGATCTGCAGAAGGATCAATGGATGCTGGAAACATTTTAAAACCAG
CCCTTGCAAGAGGTGAACTGCAGCTAGTAGGTGCGACGACATTAAAAGAATATCGCCAAATTGAAAAAGATGCTGCACTC
GAACGGCGCTTCCAGCCCGTCATCGTAGATGAGCCAACACAAGATGAAGCGATCGACATCTTAAAAGGCATTCAAGATAA
ATACGAGGCTTATCATGGCGTCACCTATTCAGATGAAGCAATCAAAGCGTGTGTTCAATTATCTTCGCGGTATATTCAAG
ACCGTCATTTACCGGATAAAGCCATTGATTTAATGGATGAAGCTGGTTCAAAAGCGAACCTCTCCATTGATGCAGCAAGT
GAAGATGAGCTGACAAATCGATTAACGGAAATTGCCGCAGAAAAACAAGCTGCGCTAAAAGAAGAACAATATGAAAAAGC
AGCGAAGCTTCGCGATGAAGAAGAAGCCATTGAAGCAAGACTTCAAAACAAAACAACTGAAAAAGAGCATATCGTTACAG
CAGAGGACATTCAGGCCATTGTGGAACAAAAAACAGGCATTCCTGTCGGGAAACTCCAAGCAGACGAACAAACCAAAATG
AAAGAGATTGACGTCCGTCTAAAAGCACGAGTGATTGGGCAGGAGCATGCGGTTGATAAAGTGGCCAAAGCCGTGAAAAG
AAGCAGAGCTGGATTAAAATCGAAACATAGACCAACAGGCTCCTTCCTTTTCGTTGGCCCAACAGGTGTCGGGAAAACCG
AATTGTCTAAAACGTTAGCTGAAGAATTATTCGGTTCAAGAGATGCGATCATTCGTTTAGATATGAGTGAGTACATGGAA
AAACACTCTGTGTCCAAACTCATCGGTTCTCCTCCTGGTTACGTTGGACATGATGAAGCTGGCCAGCTGACTGAAAAAGT
GCGCAGAAAACCATACAGCATCATTTTGCTGGATGAAATCGAAAAAGCACACCCAGATGTACAGCACATGTTCCTGCAAA
TCATGGAAGACGGCCGCTTAACAGACAGCCAAGGCAGAACGGTCAGCTTTAAAGATACAGTCATCATCATGACAAGTAAC
GCAGGCACCGCAGATAAAACAGTCAAAGTGGGCTTCCAATCTGATCAGGAAGAAGCGTTTGAGGAACAATCACTCATTGA
TTCACTGAGCAGCTACTTCAAACCAGAATTTTTGAACCGTTTTGACAGCATCATTCAATTTGATTCACTAGACAGAGAGG
ATTTAGTGAAGATTGTTGATCTTCTGCTCAATGAGCTGTCAGAGCAATTAAAAGAGCAGAATTTAACAGTTCATGTCACA
AATGAAGCAAAAGAAAAGATTGCAGAGCTTGGATATCATCCTGCATTTGGTGCTCGTCCACTTCGAAGAACCATTCAAGA
GCACGTTGAAGACCAAATGACGGAGATCCTGCTTGAAGAGGAGCAGCTTTCTGGATTTACTGTGGATGTTGAACATGACG
AAATCGTCGTAAAAAAAGGATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-687)

AAA lid domain (AAA_lid_9)

(253-353)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)

AAA domain (Cdc48 subfamily) (AAA_2)

(437-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

57.182

100

0.603
  clpE Streptococcus mutans UA159

56.604

100

0.6
  clpE Streptococcus pneumoniae Rx1

55.801

100

0.577
  clpE Streptococcus pneumoniae D39

55.801

100

0.577
  clpE Streptococcus pneumoniae R6

55.801

100

0.577
  clpE Streptococcus pneumoniae TIGR4

55.801

100

0.577
  clpC Bacillus subtilis subsp. subtilis str. 168

53.881

95.714

0.516
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.086

93.143

0.439
  clpC Streptococcus thermophilus LMD-9

46.368

92.429

0.429
  clpC Streptococcus thermophilus LMG 18311

46.213

92.429

0.427
  clpC Streptococcus mutans UA159

44.172

93.143

0.411
  clpC Streptococcus pneumoniae TIGR4

44.904

89.714

0.403
  clpC Streptococcus pneumoniae Rx1

45.104

89

0.401
  clpC Streptococcus pneumoniae D39

45.104

89

0.401

Multiple sequence alignment