Detailed information NTG0098690

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R8615_RS09215
• Genome accession: NZ_AP026929
• Coordinates: 1800069..1801106 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain PZ900701114
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1795069..1806106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8615_RS09190 (PC1101_18090)	-	1795808..1797139 (-)	1332	WP_016398203.1	hemolysin family protein	-
R8615_RS09195 (PC1101_18100)	endA	1797430..1798254 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
R8615_RS09200 (PC1101_18110)	-	1798293..1798481 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
R8615_RS09205 (PC1101_18120)	murA	1798474..1799757 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R8615_RS09210 (PC1101_18130)	-	1799781..1800011 (-)	231	WP_000250392.1	DUF1146 family protein	-
R8615_RS09215 (PC1101_18140)	sepM	1800069..1801106 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
R8615_RS09220 (PC1101_18150)	coaD	1801090..1801578 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
R8615_RS09225 (PC1101_18160)	rsmD	1801568..1802107 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R8615_RS09230 (PC1101_18170)	asnA	1802172..1803164 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R8615_RS09235 (PC1101_18180)	-	1803276..1803959 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
R8615_RS09240 (PC1101_18190)	-	1804015..1804755 (-)	741	WP_000152701.1	RNA methyltransferase	-
R8615_RS09245 (PC1101_18200)	-	1804789..1805067 (+)	279	WP_001174613.1	acylphosphatase	-
R8615_RS09250 (PC1101_18210)	yidC	1805145..1806071 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=98690 R8615_RS09215 WP_000727276.1 1800069..1801106(-) (sepM) [Streptococcus pneumoniae strain PZ900701114]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=98690 R8615_RS09215 WP_000727276.1 1800069..1801106(-) (sepM) [Streptococcus pneumoniae strain PZ900701114]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588