Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   ACOCI8_RS05880 Genome accession   NZ_CP184563
Coordinates   1217015..1217728 (-) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain SCTW2018065     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1212015..1222728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACOCI8_RS05850 (ACOCI8_05850) sph 1212392..1213218 (-) 827 Protein_1148 sphingomyelin phosphodiesterase -
  ACOCI8_RS05855 (ACOCI8_05855) - 1213275..1214312 (-) 1038 WP_000857200.1 tyrosine-type recombinase/integrase -
  ACOCI8_RS05860 (ACOCI8_05860) - 1214505..1215209 (-) 705 WP_017804779.1 type II toxin-antitoxin system PemK/MazF family toxin -
  ACOCI8_RS05865 (ACOCI8_05865) - 1215349..1215516 (-) 168 WP_000694771.1 hypothetical protein -
  ACOCI8_RS05870 (ACOCI8_05870) - 1215720..1216061 (-) 342 WP_000591749.1 hypothetical protein -
  ACOCI8_RS05875 (ACOCI8_05875) - 1216067..1216999 (-) 933 WP_096002309.1 exonuclease domain-containing protein -
  ACOCI8_RS05880 (ACOCI8_05880) irvR 1217015..1217728 (-) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  ACOCI8_RS05885 (ACOCI8_05885) - 1217691..1217865 (+) 175 Protein_1155 transcriptional regulator -
  ACOCI8_RS05890 (ACOCI8_05890) - 1217862..1218125 (+) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  ACOCI8_RS05895 (ACOCI8_05895) - 1218141..1218356 (+) 216 WP_001025404.1 Thoeris anti-defense Tad2 family protein -
  ACOCI8_RS05900 (ACOCI8_05900) - 1218345..1218674 (-) 330 WP_000128907.1 hypothetical protein -
  ACOCI8_RS05905 (ACOCI8_05905) - 1218725..1219477 (+) 753 WP_096002308.1 phage antirepressor KilAC domain-containing protein -
  ACOCI8_RS05910 (ACOCI8_05910) - 1219490..1219750 (+) 261 WP_000435343.1 hypothetical protein -
  ACOCI8_RS05915 (ACOCI8_05915) - 1219774..1219929 (-) 156 Protein_1161 hypothetical protein -
  ACOCI8_RS05920 (ACOCI8_05920) - 1219984..1220310 (+) 327 WP_001025595.1 hypothetical protein -
  ACOCI8_RS05925 (ACOCI8_05925) - 1220307..1220406 (+) 100 Protein_1163 hypothetical protein -
  ACOCI8_RS05930 (ACOCI8_05930) - 1220555..1220878 (+) 324 WP_001120201.1 DUF771 domain-containing protein -
  ACOCI8_RS05935 (ACOCI8_05935) - 1220875..1221036 (+) 162 WP_000048129.1 DUF1270 family protein -
  ACOCI8_RS05940 (ACOCI8_05940) - 1221131..1221433 (+) 303 WP_000165371.1 DUF2482 family protein -
  ACOCI8_RS05945 (ACOCI8_05945) - 1221438..1221698 (+) 261 WP_000291510.1 DUF1108 family protein -
  ACOCI8_RS05950 (ACOCI8_05950) - 1221707..1221970 (+) 264 WP_001205732.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=986827 ACOCI8_RS05880 WP_001031454.1 1217015..1217728(-) (irvR) [Staphylococcus aureus strain SCTW2018065]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=986827 ACOCI8_RS05880 WP_001031454.1 1217015..1217728(-) (irvR) [Staphylococcus aureus strain SCTW2018065]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401