Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   NST80_RS01900 Genome accession   NZ_CP152039
Coordinates   358133..359452 (+) Length   439 a.a.
NCBI ID   WP_002886638.1    Uniprot ID   -
Organism   Streptococcus sp. FSL K6-1323     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 353133..364452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS01875 (NST80_01875) - 353977..354741 (+) 765 WP_045771733.1 ABC transporter ATP-binding protein -
  NST80_RS01880 (NST80_01880) - 354741..355451 (+) 711 WP_014633927.1 ABC transporter ATP-binding protein -
  NST80_RS01885 (NST80_01885) - 355586..356245 (+) 660 WP_045771734.1 CBS and ACT domain-containing protein -
  NST80_RS01890 (NST80_01890) cysK 356424..357350 (-) 927 WP_002883742.1 cysteine synthase A -
  NST80_RS01895 (NST80_01895) - 357452..358078 (-) 627 WP_002886637.1 YigZ family protein -
  NST80_RS01900 (NST80_01900) comFA/cflA 358133..359452 (+) 1320 WP_002886638.1 DEAD/DEAH box helicase Machinery gene
  NST80_RS01905 (NST80_01905) - 359433..360095 (+) 663 WP_002886639.1 ComF family protein -
  NST80_RS01910 (NST80_01910) raiA 360174..360722 (+) 549 WP_002883786.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50753.90 Da        Isoelectric Point: 9.2418

>NTDB_id=986302 NST80_RS01900 WP_002886638.1 358133..359452(+) (comFA/cflA) [Streptococcus sp. FSL K6-1323]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKQLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLGNKGRVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
ISLEEQVRLGTLEKHHLARRFHGNPLVLPKFCWQGRLQKSLMRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTNI
LQKYLPDEKMAFVSSKSEERSTIVEKFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=986302 NST80_RS01900 WP_002886638.1 358133..359452(+) (comFA/cflA) [Streptococcus sp. FSL K6-1323]
ATGGTACCTAAAGAATATTATGGACGGCTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCATGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCAGAAATTGAATTTCCTGTTTTGAAGTGGTTAGGAGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGGAAATAAAGGTCGTGTAGCTATCGCAAGTCCTCGCGTTGATGTTTGTCGAGAGTTATTTCTACGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAATTACTAAAGTTTTACCAGAACTTTGACCTAGTAATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTACTTAACAGCGACTTCTACA
ATATCTTTGGAAGAGCAAGTTCGACTTGGAACTTTAGAAAAGCATCACCTTGCCAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGTTGGCAGGGAAGATTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCCCTTCTTTATCAGA
TAAAAAAGCAACGTAAATCCAAATTCCCTTTACTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTTACCAATATT
CTACAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCTTCAAAAAGCGAGGAGCGTTCAACTATTGTAGAGAAGTT
CCGAGAAAAAGAACTATCCATCTTAGTGACAACAACTATCCTCGAACGTGGTGTGACCTTTCCACAAGTAGATGTTTTTG
TTTGCATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATTGGGGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGGCTATCCAAATCAATGCTTCGTTGTCGAGAAGAAATAAAGGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae D39

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae R6

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae TIGR4

56.381

98.178

0.554
  comFA/cflA Streptococcus mitis NCTC 12261

55.53

98.861

0.549
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.952

95.672

0.44
  comFA Latilactobacillus sakei subsp. sakei 23K

38.303

99.317

0.38

Multiple sequence alignment