Detailed information NTG0098606

Bioinformatically predicted

Overview

• Name: rcrP
• Type: Regulator
• Locus tag: R8623_RS09050
• Genome accession: NZ_AP026928
• Coordinates: 1752976..1753797 (-)
• Length: 273 a.a.
• NCBI ID: WP_000601682.1
• Uniprot ID: A0A4K3G7N8
• Organism: Streptococcus pneumoniae strain PZ900700406
• Function: regulate competence (predicted from homology) Competence regulation

Genomic Context

Location: 1747976..1758797

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8623_RS09000 (PC0401_17490)	-	1748464..1748781 (-)	318	WP_000615776.1	thioredoxin family protein	-
R8623_RS09005 (PC0401_17500)	-	1748778..1749077 (-)	300	WP_001818001.1	DUF4651 domain-containing protein	-
R8623_RS09010	-	1749171..1749302 (+)	132	WP_001811306.1	hypothetical protein	-
R8623_RS10975	-	1749414..1749609 (-)	196	Protein_1763	cell wall-binding protein	-
R8623_RS09025 (PC0401_17510)	-	1749770..1750444 (-)	675	WP_000725750.1	LiaF transmembrane domain-containing protein	-
R8623_RS09030 (PC0401_17520)	-	1750450..1750896 (-)	447	WP_000776589.1	LytTR family DNA-binding domain-containing protein	-
R8623_RS09035	-	1751010..1751513 (-)	504	WP_000800942.1	phosphatase PAP2 family protein	-
R8623_RS09040 (PC0401_17530)	-	1751510..1751872 (-)	363	WP_000078805.1	DUF2200 domain-containing protein	-
R8623_RS09045 (PC0401_17540)	rcrQ	1751938..1752969 (-)	1032	WP_016398613.1	ABC transporter ATP-binding protein	Regulator
R8623_RS09050 (PC0401_17550)	rcrP	1752976..1753797 (-)	822	WP_000601682.1	ABC transporter permease	Regulator
R8623_RS09055 (PC0401_17560)	-	1753814..1754285 (-)	472	Protein_1770	MarR family winged helix-turn-helix transcriptional regulator	-
R8623_RS09060 (PC0401_17570)	-	1754409..1755125 (-)	717	WP_000532876.1	YebC/PmpR family DNA-binding transcriptional regulator	-
R8623_RS09065 (PC0401_17580)	ply	1756008..1757423 (-)	1416	WP_001284361.1	cholesterol-dependent cytolysin pneumolysin	-
R8623_RS09070 (PC0401_17590)	-	1757434..1757844 (-)	411	WP_016398612.1	hypothetical protein	-
R8623_RS09075 (PC0401_17600)	-	1757837..1758445 (-)	609	WP_000083614.1	hypothetical protein	-

Sequence

Protein

• Length: 273 a.a.
• Molecular weight: 30604.17 Da
• Isoelectric Point: 5.9310

>NTDB_id=98606 R8623_RS09050 WP_000601682.1 1752976..1753797(-) (rcrP) [Streptococcus pneumoniae strain PZ900700406]
MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPASMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDI
FNRVLDYSQTEIKKFSIPSLLTRTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNLFVNRLMAILNPIMMGISSGLSV
AIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM

Nucleotide

• Length: 822 bp

>NTDB_id=98606 R8623_RS09050 WP_000601682.1 1752976..1753797(-) (rcrP) [Streptococcus pneumoniae strain PZ900700406]
ATGATTTTACTAGCCATTCTCTTTACTTGCTTTTCGGTCTATCTAGAGTTGGAAGTGCCGACCTATATCTCGAAAATTAC
GGATTTGCTAGGTAGTCAAGAAACTAATTTAGATGAGTTGTGGCAGCCGGCAAGCATGATGATGGGAATGTCCTTTCTTG
CCTTCTTGTCCGTAGTTGCAGTTGGATTTTTTGCATCCCGAGTGGCGGCTTCTTATACTAGTAGGCTGAGAAGTGATATT
TTTAACCGAGTTTTGGATTACTCGCAGACAGAGATTAAGAAATTTTCAATTCCTAGCCTCTTGACGCGTACTACCAATGA
CATTACTCAAGTTCAAATGTTGATTACTATGGGCTTGCAAGTGGTAACGCGTGGTTCAATTATGGCTATCTGGGCTATTG
GGAAGATTTTAGGTCATTCAGAATACTGGCTCTGGGCCGTACTTGTGGTAGTGATTGTCAACGTCCTGATGACGACCGTT
TTGATGACGCTAGCCTTTCCAAAACAGTCCTTGATTCAGGGGTTGACAGATAAACTGAACAGTATCACTCGTGAGAGTTT
AACAGGTATTCGTGTCGTTCGTGCCTACAATGCAGAGGATTATCAAAATGAAAAATTTGCAGCAGTAAATGATGAATTGA
CCCGTTTGAATTTGTTTGTCAACCGTCTTATGGCTATTTTGAATCCTATCATGATGGGGATTTCAAGTGGTTTGAGTGTA
GCGATTTACTGGATTGGGGCCTATGTGATTAACGACGCTGCTCCGATAGCGCGTCTGCCTCTCTTTAGTGACATGATTAT
TTTCATGTCTTATGCCATGTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (3-271)

3D structure

• AlphaFold DB: A0A4K3G7N8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rcrP	Streptococcus mutans UA159	56.842	100	0.593