Detailed information NTG0098600

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8623_RS08765
• Genome accession: NZ_AP026928
• Coordinates: 1713060..1714127 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain PZ900700406
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1708060..1719127

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8623_RS08740 (PC0401_17180)	treR	1708438..1709148 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
R8623_RS08745 (PC0401_17190)	-	1709181..1709984 (-)	804	WP_024477717.1	ABC transporter ATP-binding protein	-
R8623_RS08750 (PC0401_17200)	-	1709997..1710890 (-)	894	WP_024477718.1	ABC transporter permease	-
R8623_RS08755 (PC0401_17210)	-	1710902..1711504 (-)	603	WP_024477719.1	ABC transporter substrate-binding protein	-
R8623_RS08760 (PC0401_17220)	amiF	1712123..1713049 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
R8623_RS08765 (PC0401_17230)	amiE	1713060..1714127 (-)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
R8623_RS08770 (PC0401_17240)	amiD	1714136..1715062 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R8623_RS08775 (PC0401_17250)	amiC	1715062..1716558 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
R8623_RS08780 (PC0401_17260)	amiA3	1716625..1718604 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=98600 R8623_RS08765 WP_000159556.1 1713060..1714127(-) (amiE) [Streptococcus pneumoniae strain PZ900700406]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=98600 R8623_RS08765 WP_000159556.1 1713060..1714127(-) (amiE) [Streptococcus pneumoniae strain PZ900700406]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTGACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541