Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   MHB66_RS06460 Genome accession   NZ_CP152027
Coordinates   1270430..1272532 (-) Length   700 a.a.
NCBI ID   WP_046310761.1    Uniprot ID   -
Organism   Bacillus sp. FSL L8-0167     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1265430..1277532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MHB66_RS06435 (MHB66_06435) - 1265847..1266089 (+) 243 WP_024424676.1 aspartyl-phosphate phosphatase Spo0E family protein -
  MHB66_RS06440 (MHB66_06440) - 1266136..1267641 (-) 1506 WP_034281538.1 ATP-binding protein -
  MHB66_RS06445 (MHB66_06445) - 1267846..1268301 (+) 456 WP_034281539.1 MarR family transcriptional regulator -
  MHB66_RS06450 (MHB66_06450) motB 1268495..1269265 (-) 771 WP_034281540.1 flagellar motor protein MotB -
  MHB66_RS06455 (MHB66_06455) motA 1269258..1270052 (-) 795 WP_024424680.1 flagellar motor stator protein MotA -
  MHB66_RS06460 (MHB66_06460) clpC 1270430..1272532 (-) 2103 WP_046310761.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  MHB66_RS06465 (MHB66_06465) - 1272777..1273820 (+) 1044 WP_034623360.1 membrane protein -
  MHB66_RS06470 (MHB66_06470) queC 1274096..1274752 (+) 657 WP_046310763.1 7-cyano-7-deazaguanine synthase QueC -
  MHB66_RS06475 (MHB66_06475) queD 1274753..1275193 (+) 441 WP_034281544.1 6-carboxytetrahydropterin synthase QueD -
  MHB66_RS06480 (MHB66_06480) queE 1275186..1275917 (+) 732 WP_034281545.1 7-carboxy-7-deazaguanine synthase QueE -
  MHB66_RS06485 (MHB66_06485) queF 1275933..1276430 (+) 498 WP_024426839.1 preQ(1) synthase -
  MHB66_RS06490 (MHB66_06490) - 1276894..1277262 (-) 369 WP_046310766.1 winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 700 a.a.        Molecular weight: 77933.52 Da        Isoelectric Point: 5.0332

>NTDB_id=985625 MHB66_RS06460 WP_046310761.1 1270430..1272532(-) (clpC) [Bacillus sp. FSL L8-0167]
MRCQHCQVNEATIRLNMQVNSSRSQMVLCEDCYTSLMEQSKMKMGPQLFGGSSFFSQAASHAPNMEQPKQKGLLDELGRN
LTDGANAGLIDPVIGRDEEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIASGDVPNKLKNKQIYLLDVSSLVA
NTGVRGQFEERMKQLIKELQSRKNIILFVDEIHLLVGAGSAEGSMDAGNILKPALARGELQLVGATTLKEYRQIEKDAAL
ERRFQPVIVDEPTQDEAIDILKGIQDKYEAYHGVSYSDEAIKACVQLSSRYIQDRHLPDKAIDLMDEAGSKANLSIDAAS
EDELTNRLAQIAAEKQAALKEEQYEKAAKLRDEEEAIEARLQNKTTEKEHIVTAEDIQAIVEQKTGIPVGKLQADEQTKM
KEIDVRLKARVIGQEHAVDKVAKAVKRSRAGLKSKHRPTGSFLFVGPTGVGKTELSKTLAEELFGSRDAIIRLDMSEYME
KHSVSKLIGSPPGYVGHDEAGQLTEKVRRKPYSIILLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGSADKTVKVGFQSDQEEAIEEQSLIDSLSSYFKPEFLNRFDSIIQFESLDRDDLVKIVDLLLNELSEQLKEQNLTVHVT
NEAKEKIAELGYHPAFGARPLRRTIQEHVEDQMTEILLEEEQLSGFTVDVEHDEIVVKKG

Nucleotide


Download         Length: 2103 bp        

>NTDB_id=985625 MHB66_RS06460 WP_046310761.1 1270430..1272532(-) (clpC) [Bacillus sp. FSL L8-0167]
ATGCGTTGTCAACATTGTCAAGTAAATGAAGCAACTATTCGCCTGAATATGCAAGTAAATTCGTCCCGGAGCCAAATGGT
TTTATGTGAAGACTGCTATACCTCTTTGATGGAGCAGTCAAAAATGAAAATGGGACCTCAGCTTTTTGGAGGAAGTTCAT
TCTTCTCTCAGGCAGCAAGTCATGCCCCAAACATGGAGCAGCCAAAGCAAAAAGGCTTACTCGATGAGCTTGGCCGTAAC
TTAACAGATGGAGCAAATGCTGGTTTAATTGATCCAGTCATTGGCCGAGACGAAGAAGTCGCAAGAGTCATTGAGATTTT
AAATAGAAGAAATAAAAATAACCCTGTTCTTATTGGTGAACCAGGTGTTGGGAAAACAGCGATCGCAGAAGGACTCGCGC
TCAAAATTGCGAGCGGCGATGTGCCAAATAAATTAAAGAACAAACAAATCTATTTATTAGATGTCTCCTCACTTGTCGCA
AACACAGGTGTACGCGGTCAATTTGAGGAAAGAATGAAGCAGTTAATCAAAGAACTGCAAAGCCGTAAAAATATCATCTT
ATTTGTAGATGAAATCCACCTTCTTGTGGGCGCAGGATCTGCAGAAGGATCAATGGATGCTGGAAACATTTTAAAACCAG
CCCTTGCAAGAGGCGAGCTGCAGCTAGTAGGTGCGACGACATTAAAAGAATATCGCCAAATTGAAAAAGATGCTGCACTC
GAACGGCGCTTCCAGCCCGTTATCGTAGATGAGCCAACACAAGATGAAGCAATCGACATCTTAAAAGGCATTCAAGATAA
ATACGAGGCCTATCATGGTGTCTCCTATTCAGATGAAGCAATCAAAGCGTGCGTTCAATTATCTTCGCGGTATATTCAAG
ACCGTCATTTGCCGGATAAAGCCATTGATTTAATGGATGAAGCTGGTTCAAAAGCGAATCTCTCCATTGATGCAGCAAGT
GAAGATGAGCTGACAAACCGACTAGCGCAAATTGCCGCAGAAAAACAAGCTGCGCTAAAAGAAGAACAATATGAAAAAGC
AGCGAAGCTTCGCGATGAAGAAGAAGCCATTGAAGCAAGACTTCAAAACAAAACAACTGAAAAAGAGCATATCGTTACAG
CAGAGGACATTCAGGCCATTGTGGAACAAAAAACAGGCATTCCTGTCGGGAAACTCCAAGCAGACGAACAAACCAAAATG
AAAGAAATTGACGTCCGTCTAAAAGCACGAGTGATTGGACAGGAACATGCGGTTGATAAAGTGGCGAAAGCCGTGAAAAG
AAGCAGAGCTGGTTTAAAATCGAAACATAGACCAACAGGCTCCTTCCTTTTCGTTGGACCAACAGGTGTCGGGAAAACCG
AATTGTCTAAAACGTTAGCTGAAGAATTATTCGGTTCAAGAGATGCGATCATTCGTTTAGATATGAGTGAGTACATGGAA
AAACACTCTGTGTCCAAACTCATCGGTTCTCCTCCTGGTTACGTTGGACATGATGAAGCTGGCCAGCTGACTGAAAAAGT
GCGCAGAAAACCATACAGCATCATTTTGCTGGATGAAATCGAAAAAGCACACCCAGATGTACAGCACATGTTCCTGCAAA
TCATGGAAGATGGCCGCTTAACAGACAGCCAAGGCAGAACGGTCAGCTTTAAAGATACAGTCATCATCATGACAAGTAAC
GCAGGCAGCGCAGATAAAACGGTCAAGGTCGGCTTCCAGTCTGATCAGGAAGAAGCGATTGAGGAACAATCACTCATTGA
TTCACTAAGCAGCTACTTCAAACCAGAATTTTTGAACCGTTTTGACAGCATCATTCAGTTTGAATCATTAGACAGAGATG
ATTTAGTGAAGATTGTTGATCTTCTGCTCAATGAGCTGTCAGAGCAATTAAAAGAGCAGAATTTAACAGTCCATGTCACA
AATGAAGCGAAAGAAAAAATCGCAGAGCTTGGATATCACCCTGCATTTGGTGCTCGTCCACTTCGAAGAACCATCCAAGA
GCACGTTGAAGACCAAATGACGGAGATCCTGCTTGAAGAGGAGCAGCTTTCTGGATTTACTGTGGATGTTGAACATGACG
AAATCGTCGTAAAAAAAGGATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(253-353)

AAA domain (Cdc48 subfamily) (AAA_2)

(437-604)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-687)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

56.64

100

0.597
  clpE Streptococcus mutans UA159

56.334

100

0.597
  clpE Streptococcus pneumoniae Rx1

55.525

100

0.574
  clpE Streptococcus pneumoniae D39

55.525

100

0.574
  clpE Streptococcus pneumoniae R6

55.525

100

0.574
  clpE Streptococcus pneumoniae TIGR4

55.525

100

0.574
  clpC Bacillus subtilis subsp. subtilis str. 168

53.731

95.714

0.514
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.327

90.857

0.43
  clpC Streptococcus thermophilus LMD-9

45.975

92.286

0.424
  clpC Streptococcus thermophilus LMG 18311

45.82

92.286

0.423
  clpC Streptococcus pneumoniae TIGR4

44.513

92.429

0.411
  clpC Streptococcus pneumoniae Rx1

44.704

91.714

0.41
  clpC Streptococcus pneumoniae D39

44.704

91.714

0.41
  clpC Streptococcus mutans UA159

44.15

91.571

0.404

Multiple sequence alignment