Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   MKZ22_RS06860 Genome accession   NZ_CP152009
Coordinates   1375741..1377849 (-) Length   702 a.a.
NCBI ID   WP_185106963.1    Uniprot ID   -
Organism   Bacillus sp. FSL R7-0675     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1370741..1382849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKZ22_RS06835 (MKZ22_06835) - 1371331..1371573 (+) 243 WP_065097155.1 aspartyl-phosphate phosphatase Spo0E family protein -
  MKZ22_RS06840 (MKZ22_06840) - 1371620..1373125 (-) 1506 WP_065097156.1 ATP-binding protein -
  MKZ22_RS06845 (MKZ22_06845) - 1373331..1373786 (+) 456 WP_003211701.1 MarR family transcriptional regulator -
  MKZ22_RS06850 (MKZ22_06850) motB 1373816..1374580 (-) 765 WP_106067340.1 flagellar motor protein MotB -
  MKZ22_RS06855 (MKZ22_06855) motA 1374573..1375367 (-) 795 WP_003212085.1 flagellar motor stator protein MotA -
  MKZ22_RS06860 (MKZ22_06860) clpC 1375741..1377849 (-) 2109 WP_185106963.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  MKZ22_RS06865 (MKZ22_06865) - 1378093..1379136 (+) 1044 WP_106067341.1 hypothetical protein -
  MKZ22_RS06870 (MKZ22_06870) queC 1379412..1380068 (+) 657 WP_106067342.1 7-cyano-7-deazaguanine synthase QueC -
  MKZ22_RS06875 (MKZ22_06875) queD 1380069..1380509 (+) 441 WP_044139790.1 6-carboxytetrahydropterin synthase QueD -
  MKZ22_RS06880 (MKZ22_06880) queE 1380502..1381233 (+) 732 WP_268454837.1 7-carboxy-7-deazaguanine synthase QueE -
  MKZ22_RS06885 (MKZ22_06885) queF 1381249..1381746 (+) 498 WP_106067344.1 preQ(1) synthase -
  MKZ22_RS06890 (MKZ22_06890) - 1382215..1382433 (+) 219 WP_044139792.1 hypothetical protein -
  MKZ22_RS06895 (MKZ22_06895) - 1382554..1382742 (-) 189 WP_003211747.1 DUF2187 family protein -

Sequence

Protein


Download         Length: 702 a.a.        Molecular weight: 78175.78 Da        Isoelectric Point: 5.0810

>NTDB_id=984614 MKZ22_RS06860 WP_185106963.1 1375741..1377849(-) (clpC) [Bacillus sp. FSL R7-0675]
MRCQHCQVNEATIRLNMQVNSSRSQMVLCEDCYTSLMEQSKMKMGPQLFGGSSFFSGQEQAGHTQNVEQPKQKGLLDELG
RNLTDGANAGLIDPVIGRDEEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIASGDVPNKLKNKQIYLLDVSSL
VANTGIRGQFEERMKQLIKELQSRKNIILFVDEIHLLVGAGSAEGSMDAGNILKPALARGELQLVGATTLKEYRQIEKDA
ALERRFQPVIVDEPTQAEAIEILKGIQDKYESYHGVTYSAEAIQACVQLSSRYIQDRHLPDKAIDLMDEAGSKANLSIDA
ASEDELTNRLTEIAAEKHAALKEEQYEKAAKLRDEEEAIEARLQNKTNDKEHVVTAEDIQAIVEQKTGIPVGKLQADEQT
KMKEIDVRLKARVIGQEHAVEKVAKAVKRSRAGLKSKHRPTGSFLFVGPTGVGKTELSKTLAEELFGSRDAIIRLDMSEY
MEKHSVSKLIGSPPGYVGHDEAGQLTEKVRRKPYSIILLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMT
SNAGSTDKTVKVGFQSDQEEAIEEQSLIDSLSAYFKPEFLNRFDSIIQFDSLDRDDLVKIVDLLLNELSEQLKEQNLTVH
VTKEAKEKIAELGYHPAFGARPLRRTIQEHVEDQMTEILLEEEKLSGFTVDVEDNEIVVKKG

Nucleotide


Download         Length: 2109 bp        

>NTDB_id=984614 MKZ22_RS06860 WP_185106963.1 1375741..1377849(-) (clpC) [Bacillus sp. FSL R7-0675]
ATGCGTTGTCAACATTGTCAAGTAAATGAAGCAACAATTCGCCTGAATATGCAAGTGAATTCATCCCGGAGCCAAATGGT
TTTATGTGAAGACTGCTACACCTCTTTGATGGAGCAATCAAAAATGAAAATGGGACCTCAATTGTTCGGAGGAAGCTCAT
TCTTCTCTGGGCAAGAGCAAGCAGGACATACGCAAAACGTAGAGCAGCCAAAGCAAAAAGGCTTACTCGATGAACTTGGC
CGCAATTTAACAGATGGCGCAAATGCTGGTTTAATTGATCCAGTCATCGGCCGTGATGAAGAAGTCGCAAGAGTCATTGA
GATTTTAAATAGAAGAAATAAAAACAATCCTGTCCTCATTGGTGAACCAGGTGTTGGGAAAACAGCGATCGCTGAAGGAC
TTGCACTGAAAATTGCAAGTGGCGATGTACCAAATAAATTAAAGAACAAACAAATCTATTTATTAGATGTCTCCTCCCTT
GTAGCGAATACAGGGATACGTGGTCAATTTGAGGAAAGAATGAAGCAGTTAATTAAAGAACTACAAAGCCGTAAAAATAT
TATCTTATTTGTAGATGAAATCCATCTTCTTGTAGGCGCAGGCTCTGCTGAAGGGTCAATGGATGCTGGCAACATTTTAA
AACCAGCTCTTGCACGAGGCGAGCTCCAGCTAGTAGGTGCGACGACATTAAAAGAATATCGTCAAATTGAAAAAGATGCC
GCACTTGAACGACGCTTTCAGCCCGTCATTGTAGATGAGCCAACACAAGCTGAAGCGATCGAGATTTTAAAAGGCATTCA
AGATAAGTACGAAAGCTATCATGGCGTCACCTATTCAGCGGAAGCCATTCAAGCGTGTGTTCAATTATCTTCCCGGTATA
TTCAAGACCGTCATTTGCCGGATAAAGCCATTGATTTAATGGATGAAGCAGGTTCAAAAGCGAACCTCTCCATTGATGCA
GCAAGTGAAGATGAACTAACGAATCGTCTGACAGAAATCGCTGCTGAAAAACATGCTGCTTTAAAAGAAGAACAATATGA
AAAAGCGGCGAAGCTTCGAGATGAAGAAGAAGCCATTGAAGCAAGACTTCAAAACAAAACAAATGACAAAGAACATGTCG
TCACAGCAGAAGACATTCAAGCCATTGTGGAACAAAAAACAGGCATCCCTGTCGGCAAACTGCAAGCAGACGAACAAACC
AAAATGAAAGAAATTGACGTCCGCTTAAAAGCACGAGTGATCGGCCAGGAACATGCGGTTGAAAAGGTAGCGAAAGCTGT
GAAAAGAAGCAGAGCCGGCTTAAAATCGAAACATAGACCAACTGGCTCCTTCCTTTTCGTTGGACCAACAGGTGTCGGGA
AAACCGAATTGTCGAAAACGCTAGCTGAAGAATTATTTGGTTCAAGAGATGCGATCATCCGTTTAGATATGAGTGAGTAC
ATGGAGAAACACTCAGTATCTAAGCTCATCGGTTCTCCTCCTGGTTACGTTGGACATGATGAAGCAGGCCAGCTGACAGA
AAAAGTGCGCAGAAAACCATACAGCATCATTTTGCTGGATGAAATCGAAAAAGCACATCCTGATGTGCAGCATATGTTCC
TTCAAATCATGGAAGATGGCCGGTTAACAGACAGCCAAGGCAGAACCGTCAGCTTTAAAGATACAGTCATCATCATGACA
AGTAACGCAGGCAGCACAGATAAAACGGTCAAAGTCGGCTTCCAGTCTGATCAGGAAGAAGCGATTGAAGAACAATCACT
CATTGATTCACTCAGCGCCTATTTCAAACCAGAATTTTTGAACCGTTTTGACAGCATCATTCAGTTTGACTCATTAGATC
GAGATGATTTAGTGAAGATTGTGGATCTTCTGCTCAATGAGCTGTCAGAACAATTAAAAGAGCAGAATTTGACAGTCCAT
GTGACAAAAGAAGCGAAAGAAAAAATTGCAGAACTTGGATATCATCCTGCATTTGGTGCTCGTCCACTGCGAAGAACCAT
TCAAGAGCACGTTGAAGATCAAATGACGGAAATATTGCTTGAAGAAGAAAAGCTTTCAGGATTTACTGTAGATGTTGAAG
ATAACGAAATTGTCGTAAAAAAAGGATAG

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(612-687)

AAA lid domain (AAA_lid_9)

(256-355)

AAA domain (Cdc48 subfamily) (AAA_2)

(439-606)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

56.504

100

0.594
  clpE Streptococcus mutans UA159

57.618

100

0.593
  clpE Streptococcus pneumoniae Rx1

55.249

100

0.57
  clpE Streptococcus pneumoniae D39

55.249

100

0.57
  clpE Streptococcus pneumoniae R6

55.249

100

0.57
  clpE Streptococcus pneumoniae TIGR4

55.249

100

0.57
  clpC Bacillus subtilis subsp. subtilis str. 168

53.274

95.726

0.51
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.17

90.598

0.427
  clpC Streptococcus thermophilus LMD-9

46.166

91.026

0.42
  clpC Streptococcus thermophilus LMG 18311

46.009

91.026

0.419
  clpC Streptococcus pneumoniae TIGR4

45.469

89.601

0.407
  clpC Streptococcus pneumoniae Rx1

45.673

88.889

0.406
  clpC Streptococcus pneumoniae D39

45.673

88.889

0.406
  clpC Streptococcus mutans UA159

44.603

89.744

0.4

Multiple sequence alignment