Detailed information NTG0098453

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R8559_RS09580
• Genome accession: NZ_AP026926
• Coordinates: 1844059..1845096 (-)
• Length: 345 a.a.
• NCBI ID: WP_050200217.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700119
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1839059..1850096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8559_RS09555 (PC0116_18770)	-	1839860..1841191 (-)	1332	WP_000390046.1	hemolysin family protein	-
R8559_RS09560 (PC0116_18780)	endA	1841420..1842244 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
R8559_RS09565 (PC0116_18790)	-	1842283..1842471 (-)	189	WP_050218344.1	DNA-directed RNA polymerase subunit beta	-
R8559_RS09570 (PC0116_18800)	murA	1842464..1843747 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R8559_RS09575 (PC0116_18810)	-	1843771..1844001 (-)	231	WP_000250384.1	DUF1146 family protein	-
R8559_RS09580 (PC0116_18820)	sepM	1844059..1845096 (-)	1038	WP_050200217.1	SepM family pheromone-processing serine protease	Regulator
R8559_RS09585 (PC0116_18830)	coaD	1845080..1845568 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
R8559_RS09590 (PC0116_18840)	rsmD	1845558..1846097 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R8559_RS09595 (PC0116_18850)	asnA	1846162..1847154 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R8559_RS09600 (PC0116_18860)	-	1847267..1847950 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R8559_RS09605 (PC0116_18870)	-	1848006..1848746 (-)	741	WP_000152674.1	RNA methyltransferase	-
R8559_RS09610 (PC0116_18880)	-	1848780..1849058 (+)	279	WP_001174613.1	acylphosphatase	-
R8559_RS09615 (PC0116_18890)	yidC	1849136..1850062 (+)	927	WP_000835944.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37549.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=98453 R8559_RS09580 WP_050200217.1 1844059..1845096(-) (sepM) [Streptococcus pneumoniae strain PZ900700119]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
IIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=98453 R8559_RS09580 WP_050200217.1 1844059..1845096(-) (sepM) [Streptococcus pneumoniae strain PZ900700119]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ATAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591