Detailed information NTG0098378

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: R8507_RS09805
• Genome accession: NZ_AP026925
• Coordinates: 1886444..1886746 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700097
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1881444..1891746

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8507_RS09770 (PC0094_19100)	rnpA	1882123..1882494 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R8507_RS09775	-	1882511..1882642 (-)	132	WP_000768904.1	hypothetical protein	-
R8507_RS09780 (PC0094_19110)	-	1882643..1883833 (-)	1191	WP_000167766.1	acetate kinase	-
R8507_RS09785 (PC0094_19120)	comYH	1883884..1884837 (-)	954	WP_000345100.1	class I SAM-dependent methyltransferase	Machinery gene
R8507_RS09790	-	1884898..1885492 (-)	595	Protein_1904	class I SAM-dependent methyltransferase	-
R8507_RS09795 (PC0094_19150)	comGG/cglG	1885629..1886042 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8507_RS09800 (PC0094_19160)	comGF/cglF	1886020..1886481 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8507_RS09805 (PC0094_19170)	comGE/cglE	1886444..1886746 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8507_RS09810 (PC0094_19180)	comGD/cglD	1886709..1887113 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8507_RS09815 (PC0094_19190)	comGC/cglC	1887106..1887432 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
R8507_RS09820 (PC0094_19200)	comGB/cglB	1887434..1888450 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8507_RS09825 (PC0094_19210)	comGA/cglA/cilD	1888398..1889339 (-)	942	WP_016398028.1	competence type IV pilus ATPase ComGA	Machinery gene
R8507_RS09830 (PC0094_19220)	-	1889415..1889780 (-)	366	WP_000286415.1	DUF1033 family protein	-
R8507_RS09835 (PC0094_19230)	-	1889931..1890989 (-)	1059	WP_044812807.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=98378 R8507_RS09805 WP_000413382.1 1886444..1886746(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700097]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=98378 R8507_RS09805 WP_000413382.1 1886444..1886746(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700097]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4