Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   R8635_RS05105 Genome accession   NZ_AP026924
Coordinates   966284..967093 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 961284..972093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS05085 - 962784..962909 (-) 126 WP_001818232.1 hypothetical protein -
  R8635_RS05090 (PC0062_10160) mutY 963006..964181 (+) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  R8635_RS05095 (PC0062_10170) micA 964236..964940 (+) 705 WP_000722076.1 response regulator YycF Regulator
  R8635_RS05100 (PC0062_10180) micB 964933..966282 (+) 1350 WP_050251702.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R8635_RS05105 (PC0062_10190) vicX 966284..967093 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R8635_RS05110 (PC0062_10200) relB 967184..967426 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  R8635_RS05115 (PC0062_10210) - 967428..967682 (+) 255 WP_001823540.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R8635_RS05120 (PC0062_10220) - 967729..968505 (+) 777 WP_001865265.1 potassium channel family protein -
  R8635_RS05125 (PC0062_10230) - 968761..969747 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=98260 R8635_RS05105 WP_001289493.1 966284..967093(+) (vicX) [Streptococcus pneumoniae strain PZ900700063]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=98260 R8635_RS05105 WP_001289493.1 966284..967093(+) (vicX) [Streptococcus pneumoniae strain PZ900700063]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment