Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R8625_RS09095 Genome accession   NZ_AP026923
Coordinates   1768064..1768888 (-) Length   274 a.a.
NCBI ID   WP_317649145.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1763064..1773888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS09090 (PC0054_17800) - 1766442..1767773 (-) 1332 WP_000390039.1 hemolysin family protein -
  R8625_RS09095 (PC0054_17810) endA 1768064..1768888 (-) 825 WP_317649145.1 DNA-entry nuclease EndA Machinery gene
  R8625_RS09100 (PC0054_17820) - 1768927..1769115 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  R8625_RS09105 (PC0054_17830) murA 1769108..1770391 (-) 1284 WP_317649434.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R8625_RS09110 (PC0054_17840) - 1770415..1770645 (-) 231 WP_000250393.1 DUF1146 family protein -
  R8625_RS09115 (PC0054_17850) sepM 1770703..1771740 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  R8625_RS09120 (PC0054_17860) coaD 1771724..1772212 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  R8625_RS09125 (PC0054_17870) rsmD 1772202..1772741 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R8625_RS09130 (PC0054_17880) asnA 1772806..1773798 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.62 Da        Isoelectric Point: 10.1197

>NTDB_id=98210 R8625_RS09095 WP_317649145.1 1768064..1768888(-) (endA) [Streptococcus pneumoniae strain PZ900700054]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRITLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=98210 R8625_RS09095 WP_317649145.1 1768064..1768888(-) (endA) [Streptococcus pneumoniae strain PZ900700054]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTATAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.27

100

0.993
  endA Streptococcus pneumoniae D39

99.27

100

0.993
  endA Streptococcus pneumoniae R6

99.27

100

0.993
  endA Streptococcus pneumoniae TIGR4

99.27

100

0.993

Multiple sequence alignment