Detailed information NTG0980967

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AAFV99_RS08925
• Genome accession: NZ_CP151815
• Coordinates: 1763465..1764508 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain PS006-42
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1758465..1769508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAFV99_RS08895 (AAFV99_08895)	-	1758891..1759001 (+)	111	WP_001790257.1	hypothetical protein	-
AAFV99_RS08900 (AAFV99_08900)	-	1759030..1759443 (+)	414	WP_001566709.1	hypothetical protein	-
AAFV99_RS08905 (AAFV99_08905)	-	1759874..1760860 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
AAFV99_RS08910 (AAFV99_08910)	map	1761391..1762149 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AAFV99_RS08915 (AAFV99_08915)	-	1762366..1762752 (+)	387	WP_001110179.1	hypothetical protein	-
AAFV99_RS08920 (AAFV99_08920)	liaF	1762767..1763468 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AAFV99_RS08925 (AAFV99_08925)	vraS	1763465..1764508 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AAFV99_RS08930 (AAFV99_08930)	vraR	1764498..1765127 (+)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
AAFV99_RS08935 (AAFV99_08935)	-	1765239..1766450 (-)	1212	Protein_1718	YihY/virulence factor BrkB family protein	-
AAFV99_RS08940 (AAFV99_08940)	-	1766733..1767008 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
AAFV99_RS08945 (AAFV99_08945)	-	1767015..1767479 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AAFV99_RS08950 (AAFV99_08950)	-	1767626..1767826 (+)	201	WP_000180460.1	DUF1128 family protein	-
AAFV99_RS08955 (AAFV99_08955)	-	1767829..1769085 (+)	1257	WP_072419726.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=980967 AAFV99_RS08925 WP_001017131.1 1763465..1764508(+) (vraS) [Staphylococcus aureus strain PS006-42]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=980967 AAFV99_RS08925 WP_001017131.1 1763465..1764508(+) (vraS) [Staphylococcus aureus strain PS006-42]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1