Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R9C51_RS09645 Genome accession   NZ_AP026921
Coordinates   1864576..1865400 (-) Length   274 a.a.
NCBI ID   WP_061816961.1    Uniprot ID   A0AAQ2VZP6
Organism   Streptococcus pneumoniae strain PZ900700027     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1859576..1870400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R9C51_RS09640 (PC0027_18950) - 1862954..1864285 (-) 1332 WP_317826766.1 hemolysin family protein -
  R9C51_RS09645 (PC0027_18960) endA 1864576..1865400 (-) 825 WP_061816961.1 DNA-entry nuclease EndA Machinery gene
  R9C51_RS09650 (PC0027_18970) - 1865439..1865627 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  R9C51_RS09655 (PC0027_18980) murA 1865620..1866903 (-) 1284 WP_000358035.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R9C51_RS09660 (PC0027_18990) - 1866927..1867157 (-) 231 WP_001809307.1 DUF1146 family protein -
  R9C51_RS09665 (PC0027_19000) sepM 1867215..1868252 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  R9C51_RS09670 (PC0027_19010) coaD 1868236..1868724 (-) 489 WP_001280736.1 pantetheine-phosphate adenylyltransferase -
  R9C51_RS09675 (PC0027_19020) rsmD 1868714..1869253 (-) 540 WP_044788620.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R9C51_RS09680 (PC0027_19030) asnA 1869318..1870310 (-) 993 WP_044791888.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29925.58 Da        Isoelectric Point: 10.1197

>NTDB_id=98056 R9C51_RS09645 WP_061816961.1 1864576..1865400(-) (endA) [Streptococcus pneumoniae strain PZ900700027]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKNQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=98056 R9C51_RS09645 WP_061816961.1 1864576..1865400(-) (endA) [Streptococcus pneumoniae strain PZ900700027]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAACCAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment