Detailed information NTG0098026

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: R9C51_RS04765
• Genome accession: NZ_AP026921
• Coordinates: 917498..919738 (+)
• Length: 746 a.a.
• NCBI ID: WP_050080727.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700027
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 912498..924738

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R9C51_RS04735 (PC0027_09340)	-	912648..913616 (+)	969	WP_000658183.1	PhoH family protein	-
R9C51_RS04740 (PC0027_09350)	-	913809..914309 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
R9C51_RS04745 (PC0027_09360)	-	914312..914638 (+)	327	Protein_937	TfoX/Sxy family protein	-
R9C51_RS04750 (PC0027_09380)	ald	914939..916050 (-)	1112	Protein_938	alanine dehydrogenase	-
R9C51_RS04755 (PC0027_09390)	-	916227..916796 (+)	570	WP_044791155.1	GNAT family N-acetyltransferase	-
R9C51_RS04760 (PC0027_09400)	comEA/celA/cilE	916864..917514 (+)	651	WP_044791158.1	ComEA family DNA-binding protein	Machinery gene
R9C51_RS04765 (PC0027_09410)	comEC/celB	917498..919738 (+)	2241	WP_050080727.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R9C51_RS04770 (PC0027_09420)	-	919917..920105 (+)	189	WP_023396236.1	hypothetical protein	-
R9C51_RS04775 (PC0027_09430)	-	920137..920724 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
R9C51_RS04780 (PC0027_09440)	-	920728..921912 (+)	1185	WP_000655949.1	ABC transporter permease	-
R9C51_RS04785 (PC0027_09450)	infC	922220..922750 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
R9C51_RS04790 (PC0027_09460)	rpmI	922783..922983 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
R9C51_RS04795 (PC0027_09470)	rplT	923035..923394 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
R9C51_RS04800 (PC0027_09480)	-	923452..923832 (+)	381	WP_050080729.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84508.04 Da
• Isoelectric Point: 9.5807

>NTDB_id=98026 R9C51_RS04765 WP_050080727.1 917498..919738(+) (comEC/celB) [Streptococcus pneumoniae strain PZ900700027]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGVDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=98026 R9C51_RS04765 WP_050080727.1 917498..919738(+) (comEC/celB) [Streptococcus pneumoniae strain PZ900700027]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGTATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGCAGTTTGAAGCA
GAAGGAATTTGTGGCAGAACTACAGACGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGACACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGGTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.855	100	0.979
comEC/celB	Streptococcus pneumoniae D39	97.587	100	0.976
comEC/celB	Streptococcus pneumoniae R6	97.587	100	0.976
comEC/celB	Streptococcus pneumoniae Rx1	97.587	100	0.976
comEC/celB	Streptococcus mitis NCTC 12261	92.215	99.866	0.921
comEC/celB	Streptococcus mitis SK321	92.091	100	0.921
comEC	Lactococcus lactis subsp. cremoris KW2	44.669	99.33	0.444