Detailed information NTG0097978

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R8566_RS09960
• Genome accession: NZ_AP026920
• Coordinates: 1921387..1922424 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727273.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700014
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1916387..1927424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8566_RS09935 (PC0014_19700)	-	1917188..1918519 (-)	1332	WP_000390049.1	hemolysin family protein	-
R8566_RS09940 (PC0014_19710)	endA	1918748..1919572 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
R8566_RS09945 (PC0014_19720)	-	1919611..1919799 (-)	189	WP_013315459.1	DNA-directed RNA polymerase subunit beta	-
R8566_RS09950 (PC0014_19730)	murA	1919792..1921075 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R8566_RS09955 (PC0014_19740)	-	1921099..1921329 (-)	231	WP_000250392.1	DUF1146 family protein	-
R8566_RS09960 (PC0014_19750)	sepM	1921387..1922424 (-)	1038	WP_000727273.1	SepM family pheromone-processing serine protease	Regulator
R8566_RS09965 (PC0014_19760)	coaD	1922408..1922896 (-)	489	WP_001280764.1	pantetheine-phosphate adenylyltransferase	-
R8566_RS09970 (PC0014_19770)	rsmD	1922886..1923425 (-)	540	WP_000706966.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R8566_RS09975 (PC0014_19780)	asnA	1923490..1924482 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
R8566_RS09980 (PC0014_19790)	-	1924594..1925277 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R8566_RS09985 (PC0014_19800)	-	1925333..1926073 (-)	741	WP_000152680.1	RNA methyltransferase	-
R8566_RS09990 (PC0014_19810)	-	1926107..1926385 (+)	279	WP_001174613.1	acylphosphatase	-
R8566_RS09995 (PC0014_19820)	yidC	1926463..1927389 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37519.54 Da
• Isoelectric Point: 5.0724

>NTDB_id=97978 R8566_RS09960 WP_000727273.1 1921387..1922424(-) (sepM) [Streptococcus pneumoniae strain PZ900700014]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=97978 R8566_RS09960 WP_000727273.1 1921387..1922424(-) (sepM) [Streptococcus pneumoniae strain PZ900700014]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588