Detailed information NTG0978736

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACM6AC_RS12985
• Genome accession: NZ_CP181150
• Coordinates: 2604381..2606489 (+)
• Length: 702 a.a.
• NCBI ID: WP_154284426.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain AG21-0600
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2599381..2611489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AC_RS12960 (ACM6AC_12960)	-	2599451..2599669 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
ACM6AC_RS12965 (ACM6AC_12965)	-	2600058..2600489 (+)	432	WP_000455858.1	CHAP domain-containing protein	-
ACM6AC_RS12970 (ACM6AC_12970)	-	2600628..2601905 (-)	1278	WP_154284429.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACM6AC_RS12975 (ACM6AC_12975)	-	2602160..2603326 (+)	1167	WP_154284428.1	hydroxymethylglutaryl-CoA synthase	-
ACM6AC_RS12980 (ACM6AC_12980)	-	2603497..2604018 (-)	522	WP_416152408.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
ACM6AC_RS12985 (ACM6AC_12985)	clpE	2604381..2606489 (+)	2109	WP_154284426.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
ACM6AC_RS12990 (ACM6AC_12990)	-	2606556..2606726 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
ACM6AC_RS12995 (ACM6AC_12995)	feoB	2606739..2608733 (-)	1995	WP_154284425.1	ferrous iron transport protein B	-
ACM6AC_RS13000 (ACM6AC_13000)	-	2608745..2608972 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78051.53 Da
• Isoelectric Point: 4.6910

>NTDB_id=978736 ACM6AC_RS12985 WP_154284426.1 2604381..2606489(+) (clpE) [Staphylococcus aureus strain AG21-0600]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSVEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVGGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSDEEYKKADDIQNEIRSLQDKLENNNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=978736 ACM6AC_RS12985 WP_154284426.1 2604381..2606489(+) (clpE) [Staphylococcus aureus strain AG21-0600]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAGGGTGGTAATC
ATTCTGTCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAGGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGGGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGGAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACTGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TACCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTGCTGGTTAACGAACCAAGCGCAAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGACGACGTATTAAAAG
CATGTGTTGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGTCCAGCTATTGATAAAGTTGCTACTGAAAAACGTATTTCTGAATTGGAACATGATAAACG
TAAAGCGGTAAGTGATGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATCAGATCTCTACAAGATAAATTAGAAA
ACAATAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCTCGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATATTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGATATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTACTATTTAGATCATACTGACGTTAAACATGTGGATTTAGATATCGAGGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• AAA lid domain (AAA_lid_9) (264-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.297	92.023	0.444
clpC	Lactococcus lactis subsp. cremoris KW2	46.203	90.028	0.416
clpE	Streptococcus pneumoniae TIGR4	47.249	88.034	0.416
clpE	Streptococcus pneumoniae R6	47.317	87.607	0.415
clpE	Streptococcus pneumoniae D39	47.317	87.607	0.415
clpE	Streptococcus pneumoniae Rx1	47.317	87.607	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	43.969	93.305	0.41
clpC	Streptococcus thermophilus LMD-9	44.64	89.031	0.397
clpC	Streptococcus thermophilus LMG 18311	44.48	89.031	0.396
clpC	Streptococcus pneumoniae TIGR4	44.32	89.031	0.395
clpC	Streptococcus pneumoniae Rx1	44.32	89.031	0.395
clpC	Streptococcus pneumoniae D39	44.32	89.031	0.395
clpC	Streptococcus mutans UA159	43.252	87.607	0.379
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.376	88.746	0.376