Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | MGAS37642_RS00760 | Genome accession | NZ_CP151468 |
| Coordinates | 111792..112745 (+) | Length | 317 a.a. |
| NCBI ID | WP_010921802.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain MGAS37642 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 106792..117745
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGAS37642_RS00720 (MGAS37642_00292) | - | 107619..107984 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| MGAS37642_RS00725 (MGAS37642_00294) | comYA | 108077..109015 (+) | 939 | WP_010921798.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| MGAS37642_RS00730 (MGAS37642_00296) | comYB | 108951..109985 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| MGAS37642_RS00735 (MGAS37642_00298) | comYC | 109987..110313 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| MGAS37642_RS00740 (MGAS37642_00300) | comGD | 110288..110716 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| MGAS37642_RS00745 (MGAS37642_00302) | comGE | 110673..110957 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | - |
| MGAS37642_RS00750 (MGAS37642_00304) | comYF | 110950..111384 (+) | 435 | WP_010921800.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| MGAS37642_RS00755 (MGAS37642_00306) | comGG | 111368..111694 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| MGAS37642_RS00760 (MGAS37642_00308) | comYH | 111792..112745 (+) | 954 | WP_010921802.1 | class I SAM-dependent methyltransferase | Machinery gene |
| MGAS37642_RS00765 (MGAS37642_00310) | - | 112804..114000 (+) | 1197 | WP_010921803.1 | acetate kinase | - |
| MGAS37642_RS00770 | - | 114187..114495 (+) | 309 | WP_010921804.1 | hypothetical protein | - |
| MGAS37642_RS00775 (MGAS37642_00312) | proC | 114578..115348 (-) | 771 | WP_010921805.1 | pyrroline-5-carboxylate reductase | - |
| MGAS37642_RS00780 (MGAS37642_00314) | pepA | 115396..116463 (-) | 1068 | WP_010921806.1 | glutamyl aminopeptidase | - |
| MGAS37642_RS00785 (MGAS37642_00316) | - | 116928..117212 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| MGAS37642_RS00790 (MGAS37642_00318) | - | 117209..117526 (+) | 318 | WP_011285355.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36015.10 Da Isoelectric Point: 4.7205
>NTDB_id=978477 MGAS37642_RS00760 WP_010921802.1 111792..112745(+) (comYH) [Streptococcus pyogenes strain MGAS37642]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=978477 MGAS37642_RS00760 WP_010921802.1 111792..112745(+) (comYH) [Streptococcus pyogenes strain MGAS37642]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
65.823 |
99.685 |
0.656 |
| comYH | Streptococcus mutans UA140 |
65.506 |
99.685 |
0.653 |