Detailed information NTG0978228

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS37823_RS07465
• Genome accession: NZ_CP151463
• Coordinates: 1452113..1452838 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS37823
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1447113..1457838

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37823_RS07430 (MGAS37823_03048)	-	1447247..1447630 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
MGAS37823_RS07435 (MGAS37823_03050)	-	1447641..1448192 (+)	552	WP_002988670.1	hypothetical protein	-
MGAS37823_RS07440 (MGAS37823_03052)	-	1448309..1449388 (+)	1080	WP_002988667.1	site-specific integrase	-
MGAS37823_RS07450 (MGAS37823_03056)	trmB	1449586..1450221 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS37823_RS07455 (MGAS37823_03058)	ccrZ	1450221..1451012 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS37823_RS07460 (MGAS37823_03060)	-	1451076..1452110 (-)	1035	WP_010922583.1	ABC transporter permease	-
MGAS37823_RS07465 (MGAS37823_03062)	pptA	1452113..1452838 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS37823_RS07470 (MGAS37823_03064)	-	1452910..1453329 (+)	420	WP_002983376.1	HIT family protein	-
MGAS37823_RS07475 (MGAS37823_03066)	-	1453326..1453682 (+)	357	WP_002988657.1	hypothetical protein	-
MGAS37823_RS07480 (MGAS37823_03068)	brpA	1453793..1455067 (-)	1275	WP_010922584.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS37823_RS07485 (MGAS37823_03070)	-	1455076..1455600 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
MGAS37823_RS07490 (MGAS37823_03072)	tsaE	1455575..1456036 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS37823_RS07495 (MGAS37823_03074)	-	1456190..1457650 (-)	1461	WP_011285677.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=978228 MGAS37823_RS07465 WP_002983379.1 1452113..1452838(-) (pptA) [Streptococcus pyogenes strain MGAS37823]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=978228 MGAS37823_RS07465 WP_002983379.1 1452113..1452838(-) (pptA) [Streptococcus pyogenes strain MGAS37823]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714