Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ACM6AQ_RS06035 Genome accession   NZ_CP181136
Coordinates   1244331..1246340 (+) Length   669 a.a.
NCBI ID   WP_072491557.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0619     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1239331..1251340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AQ_RS06020 (ACM6AQ_06020) - 1240514..1240879 (+) 366 WP_416152872.1 RicAFT regulatory complex protein RicA family protein -
  ACM6AQ_RS06025 (ACM6AQ_06025) thiW 1240906..1241397 (+) 492 WP_000842277.1 energy coupling factor transporter S component ThiW -
  ACM6AQ_RS06030 (ACM6AQ_06030) hexA 1241700..1244318 (+) 2619 WP_072491556.1 DNA mismatch repair protein MutS Machinery gene
  ACM6AQ_RS06035 (ACM6AQ_06035) hexB 1244331..1246340 (+) 2010 WP_072491557.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACM6AQ_RS06040 (ACM6AQ_06040) - 1246346..1246888 (+) 543 WP_098817806.1 glycerol-3-phosphate responsive antiterminator -
  ACM6AQ_RS06045 (ACM6AQ_06045) - 1247363..1248181 (+) 819 WP_001103747.1 MIP/aquaporin family protein -
  ACM6AQ_RS06050 (ACM6AQ_06050) glpK 1248310..1249806 (+) 1497 WP_061742436.1 glycerol kinase GlpK -

Sequence

Protein


Download         Length: 669 a.a.        Molecular weight: 76895.09 Da        Isoelectric Point: 5.0107

>NTDB_id=978069 ACM6AQ_RS06035 WP_072491557.1 1244331..1246340(+) (hexB) [Staphylococcus aureus strain AG21-0619]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISVEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSYPEIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSRPFMAENQNDEIVIKEDSYNPFV
TKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDDTSVQNYENKASDDYYDVNDIKGTKSKDPKRRIPY
MEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIM
LEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREA
EDPFTCPHGRPIIINFSKYELEKLFKRVM

Nucleotide


Download         Length: 2010 bp        

>NTDB_id=978069 ACM6AQ_RS06035 WP_072491557.1 1244331..1246340(+) (hexB) [Staphylococcus aureus strain AG21-0619]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCGTTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATA
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAACAGAATGGCAATGAGTTATCCGGAGATTCGAATAGC
ACTCATTTCAGATGGTAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGTTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCACCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATATCAATTGATAGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCGAAAAAAAATAAAGTGTTACA
TTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAG
AAAGTAACAGTAGGCCATTTATGGCAGAAAATCAAAACGATGAGATAGTTATAAAAGAAGATTCATATAATCCATTCGTA
ACGAAAACGTCTGAAAGTTTAATAGCTGATGATGAATCTTCCGGTTATAATAATACACGTGAAAAAGATGAAGACTACTT
CAAAAAACAACAAGAAATTTTACAAGAAATGGATCAAACATTTGATTCAAATGACGATACATCTGTGCAAAATTATGAGA
ATAAAGCGTCCGATGATTATTATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGCCAAGTACATGGAACGTATATTATTGCTCAAAATGAATTTGGCATGTACATGATTGACCAGCATGC
AGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAAATAGGTGAAGTTACCAATGAAGTACAAGATTTATTAATCC
CGTTAACATTTCATTTTTCAAAAGATGAACAATTAGTCATTGATCAATATAAAAATGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAAGATGAAGTAGAAGAAATTAT
TAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAAGTAGATATCAAAAAATTACGTGAAGATGTAGCAATCATGATGT
CATGTAAAAAATCTATTAAAGCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGGCGTCCAATTATCATTAATTTTTCAAAATACGAATTAGAAAAATTATTTAAGCG
TGTGATGTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

MutL C terminal dimerisation domain (MutL_C)

(483-625)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

40.68

100

0.411

Multiple sequence alignment