Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACM6EM_RS10850 Genome accession   NZ_CP181134
Coordinates   2157472..2158188 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   P0A0I7
Organism   Staphylococcus aureus strain AG21-0594     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2152472..2163188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6EM_RS10820 (ACM6EM_10820) - 2152691..2153317 (+) 627 WP_000522384.1 nitroreductase family protein -
  ACM6EM_RS10825 (ACM6EM_10825) - 2153678..2154463 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  ACM6EM_RS10830 (ACM6EM_10830) hld 2155060..2155140 (-) 81 WP_000046022.1 delta-hemolysin -
  ACM6EM_RS10835 (ACM6EM_10835) agrB 2155430..2155999 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  ACM6EM_RS10840 (ACM6EM_10840) agrD 2155996..2156136 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACM6EM_RS10845 (ACM6EM_10845) agrC 2156161..2157453 (+) 1293 WP_001549202.1 quorum-sensing sensor histidine kinase AgrC -
  ACM6EM_RS10850 (ACM6EM_10850) agrA 2157472..2158188 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACM6EM_RS10855 (ACM6EM_10855) - 2158260..2158367 (+) 108 WP_001790167.1 hypothetical protein -
  ACM6EM_RS10860 (ACM6EM_10860) - 2158555..2159514 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  ACM6EM_RS10865 (ACM6EM_10865) - 2159511..2160995 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  ACM6EM_RS10870 (ACM6EM_10870) - 2161144..2162094 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=978019 ACM6EM_RS10850 WP_000688492.1 2157472..2158188(+) (agrA) [Staphylococcus aureus strain AG21-0594]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=978019 ACM6EM_RS10850 WP_000688492.1 2157472..2158188(+) (agrA) [Staphylococcus aureus strain AG21-0594]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3BS1
  PDB 4G4K

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment