Detailed information NTG0977665

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ACM6AE_RS10220
• Genome accession: NZ_CP181124
• Coordinates: 2058844..2059551 (+)
• Length: 235 a.a.
• NCBI ID: WP_000094093.1
• Uniprot ID: A0A1D4DWM6
• Organism: Staphylococcus aureus strain AG21-0604
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2053844..2064551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AE_RS10175 (ACM6AE_10175)	-	2055425..2055688 (-)	264	WP_001205732.1	hypothetical protein	-
ACM6AE_RS10180 (ACM6AE_10180)	-	2055697..2055957 (-)	261	WP_416152691.1	DUF1108 family protein	-
ACM6AE_RS10185 (ACM6AE_10185)	-	2056051..2056212 (-)	162	WP_000066026.1	DUF1270 family protein	-
ACM6AE_RS10190 (ACM6AE_10190)	-	2056392..2056622 (+)	231	WP_000395457.1	hypothetical protein	-
ACM6AE_RS10195 (ACM6AE_10195)	-	2056597..2056773 (-)	177	WP_001094937.1	hypothetical protein	-
ACM6AE_RS10200 (ACM6AE_10200)	-	2056798..2057541 (-)	744	WP_086163073.1	phage antirepressor KilAC domain-containing protein	-
ACM6AE_RS10205 (ACM6AE_10205)	-	2057598..2058137 (+)	540	WP_000351243.1	hypothetical protein	-
ACM6AE_RS10210 (ACM6AE_10210)	-	2058161..2058421 (-)	261	WP_000435341.1	transcriptional regulator	-
ACM6AE_RS10215 (ACM6AE_10215)	-	2058434..2058673 (-)	240	WP_000548578.1	helix-turn-helix transcriptional regulator	-
ACM6AE_RS10220 (ACM6AE_10220)	irvR	2058844..2059551 (+)	708	WP_000094093.1	helix-turn-helix domain-containing protein	Regulator
ACM6AE_RS10225 (ACM6AE_10225)	-	2059563..2059718 (+)	156	WP_001049399.1	hypothetical protein	-
ACM6AE_RS10230 (ACM6AE_10230)	-	2059705..2059890 (+)	186	WP_001089804.1	hypothetical protein	-
ACM6AE_RS10235 (ACM6AE_10235)	-	2060090..2060257 (+)	168	WP_000705238.1	hypothetical protein	-
ACM6AE_RS10240 (ACM6AE_10240)	-	2060479..2061078 (+)	600	WP_164787765.1	type II toxin-antitoxin system PemK/MazF family toxin	-
ACM6AE_RS10245 (ACM6AE_10245)	-	2061285..2062670 (+)	1386	WP_000861313.1	recombinase family protein	-
ACM6AE_RS10250 (ACM6AE_10250)	-	2062662..2063348 (-)	687	Protein_1985	SLC13 family permease	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26769.35 Da
• Isoelectric Point: 5.4082

>NTDB_id=977665 ACM6AE_RS10220 WP_000094093.1 2058844..2059551(+) (irvR) [Staphylococcus aureus strain AG21-0604]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide

• Length: 708 bp

>NTDB_id=977665 ACM6AE_RS10220 WP_000094093.1 2058844..2059551(+) (irvR) [Staphylococcus aureus strain AG21-0604]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACACCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (123-234)

• Helix-turn-helix (HTH_3) (8-61)

3D structure

• AlphaFold DB: A0A1D4DWM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	30.769	100	0.374