Detailed information NTG0977165

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS37854_RS07475
• Genome accession: NZ_CP151444
• Coordinates: 1456087..1456812 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS37854
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1451087..1461812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37854_RS07440 (MGAS37854_03054)	-	1451221..1451604 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
MGAS37854_RS07445 (MGAS37854_03056)	-	1451615..1452166 (+)	552	WP_002988670.1	hypothetical protein	-
MGAS37854_RS07450 (MGAS37854_03058)	-	1452283..1453362 (+)	1080	WP_002988667.1	site-specific integrase	-
MGAS37854_RS07460 (MGAS37854_03062)	trmB	1453560..1454195 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS37854_RS07465 (MGAS37854_03064)	ccrZ	1454195..1454986 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS37854_RS07470 (MGAS37854_03066)	-	1455050..1456084 (-)	1035	WP_010922583.1	ABC transporter permease	-
MGAS37854_RS07475 (MGAS37854_03068)	pptA	1456087..1456812 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS37854_RS07480 (MGAS37854_03070)	-	1456884..1457303 (+)	420	WP_002983376.1	HIT family protein	-
MGAS37854_RS07485 (MGAS37854_03072)	-	1457300..1457656 (+)	357	WP_002988657.1	hypothetical protein	-
MGAS37854_RS07490 (MGAS37854_03074)	brpA	1457767..1459041 (-)	1275	WP_010922584.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS37854_RS07495 (MGAS37854_03076)	-	1459050..1459574 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
MGAS37854_RS07500 (MGAS37854_03078)	tsaE	1459549..1460010 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS37854_RS07505 (MGAS37854_03080)	-	1460164..1461624 (-)	1461	WP_011285677.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=977165 MGAS37854_RS07475 WP_002983379.1 1456087..1456812(-) (pptA) [Streptococcus pyogenes strain MGAS37854]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=977165 MGAS37854_RS07475 WP_002983379.1 1456087..1456812(-) (pptA) [Streptococcus pyogenes strain MGAS37854]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714