Detailed information NTG0976867

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AN_RS10490
• Genome accession: NZ_CP181102
• Coordinates: 2086491..2087534 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: Q99SZ7
• Organism: Staphylococcus aureus strain AG21-0614
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2081491..2092534

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AN_RS10460 (ACM6AN_10460)	-	2081912..2083168 (-)	1257	WP_001795108.1	aminopeptidase	-
ACM6AN_RS10465 (ACM6AN_10465)	-	2083171..2083371 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACM6AN_RS10470 (ACM6AN_10470)	-	2083518..2083982 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AN_RS10475 (ACM6AN_10475)	-	2083989..2084264 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6AN_RS10480 (ACM6AN_10480)	-	2084542..2085759 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACM6AN_RS10485 (ACM6AN_10485)	vraR	2085872..2086501 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACM6AN_RS10490 (ACM6AN_10490)	vraS	2086491..2087534 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AN_RS10495 (ACM6AN_10495)	liaF	2087531..2088232 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AN_RS10500 (ACM6AN_10500)	-	2088247..2088633 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6AN_RS10505 (ACM6AN_10505)	map	2088850..2089608 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACM6AN_RS10510 (ACM6AN_10510)	-	2090139..2091125 (+)	987	WP_000999717.1	FUSC family protein	-
ACM6AN_RS10515 (ACM6AN_10515)	-	2091556..2091969 (-)	414	WP_078135150.1	hypothetical protein	-
ACM6AN_RS10520 (ACM6AN_10520)	-	2091998..2092108 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=976867 ACM6AN_RS10490 WP_001017131.1 2086491..2087534(-) (vraS) [Staphylococcus aureus strain AG21-0614]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=976867 ACM6AN_RS10490 WP_001017131.1 2086491..2087534(-) (vraS) [Staphylococcus aureus strain AG21-0614]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: Q99SZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1