Detailed information NTG0976862

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MGAS38337_RS02350
• Genome accession: NZ_CP151439
• Coordinates: 438843..439844 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS38337
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 433843..444844

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS38337_RS02325 (MGAS38337_00958)	-	434517..435200 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
MGAS38337_RS02330 (MGAS38337_00960)	-	435411..436337 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
MGAS38337_RS02335 (MGAS38337_00962)	-	436482..436859 (-)	378	WP_002985686.1	VOC family protein	-
MGAS38337_RS02340 (MGAS38337_00964)	-	436870..437535 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
MGAS38337_RS02345 (MGAS38337_00966)	-	437584..438669 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
MGAS38337_RS02350 (MGAS38337_00968)	ccpA	438843..439844 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
MGAS38337_RS02355 (MGAS38337_00970)	-	439975..440973 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
MGAS38337_RS02360 (MGAS38337_00972)	-	440975..442309 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
MGAS38337_RS02365 (MGAS38337_00974)	thrS	442731..444674 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=976862 MGAS38337_RS02350 WP_002985680.1 438843..439844(+) (ccpA) [Streptococcus pyogenes strain MGAS38337]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=976862 MGAS38337_RS02350 WP_002985680.1 438843..439844(+) (ccpA) [Streptococcus pyogenes strain MGAS38337]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559