Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8522_RS11265 Genome accession   NZ_AP026916
Coordinates   2190095..2190757 (+) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2185095..2195757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS11245 (PC0006_22250) cysK 2185196..2186116 (-) 921 WP_000029866.1 cysteine synthase A -
  R8522_RS11250 (PC0006_22260) - 2186382..2187728 (+) 1347 WP_001860172.1 IS1380-like element ISSpn5 family transposase -
  R8522_RS11255 (PC0006_22270) - 2188109..2188744 (-) 636 WP_000395739.1 YigZ family protein -
  R8522_RS11260 (PC0006_22280) comFA/cflA 2188800..2190098 (+) 1299 WP_050123028.1 DEAD/DEAH box helicase Machinery gene
  R8522_RS11265 (PC0006_22290) comFC/cflB 2190095..2190757 (+) 663 WP_000649971.1 ComF family protein Machinery gene
  R8522_RS11270 (PC0006_22300) hpf 2190837..2191385 (+) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8522_RS11275 (PC0006_22310) - 2191521..2193494 (+) 1974 WP_000715109.1 DHH family phosphoesterase -
  R8522_RS11280 (PC0006_22320) rplI 2193491..2193943 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  R8522_RS11285 (PC0006_22330) dnaB 2193987..2195339 (+) 1353 WP_000852486.1 replicative DNA helicase -
  R8522_RS11290 (PC0006_22340) - 2195341..2195607 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=97683 R8522_RS11265 WP_000649971.1 2190095..2190757(+) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700006]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=97683 R8522_RS11265 WP_000649971.1 2190095..2190757(+) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700006]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment